Art

J-GLOBAL ID：202002260509091010   Reference number：20A2091166

Interaction between SDF1 and CXCR4 Promotes Photoreceptor Differentiation via Upregulation of NFκB Pathway Signaling Activity in Pax6 Gene-Transfected Photoreceptor Precursors

SDF1とCXCR4の相互作用はPax6遺伝子導入光受容体前駆体におけるNFκB経路シグナリング活性のアップレギュレーションを介して光受容体分化を促進する【JST・京大機械翻訳】

Author (10)： Shimizu Jun (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Suzuki Tomoko (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Hirotsu Chieko (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Ueno Hiroki (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Takada Erika (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Arimitsu Nagisa (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Ueda Yuji (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Wakisaka Sueshige (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Suzuki Noboru (Departments of Immunology and Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Suzuki Noboru (Department of Regenerative Medicine, St. Marianna University Graduate School of Medicine, Kawasaki, Japan)
Material： Ophthalmic Research
Volume： 63  Issue： 4  Page： 392-403  Publication year： 2020 
JST Material Number： W6353A  ISSN： 0030-3747  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Background: CCL2 (also known a...

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Thesaurus term： *interaction ,  Retina ,  mRNA ,  cell culture ,  neonate ,  human ,  *differentiation (biology) ,  luciferase ,  rhodopsin ,  *photoreceptor ,  promoter (genetics) ,  clone ,  *Up-Regulation ,  induced pluripotent stem cell ,  committed stem cell

Author keywords (6)： iPS cell ,  Retinal neuron ,  Differentiation ,  Transcription factor ,  SDF1 ,  CXCR4

JST classification (2)： Visual sense  (EJ13020B) ,  Cell physiology in general  (EF02010S)

Terms in the title (13)： SDF1 ,  CXCR4 ,  相互作用 ,  Pax6遺伝子 ,  光受容体 ,  前駆体 ,  NFκB ,  経路 ,  シグナリング ,  活性 ,  アップレギュレーション ,  分化 ,  促進