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J-GLOBAL ID：202002261044974795   Reference number：20A0575035

ALDH4A1 expression levels are elevated in postmortem brains of patients with schizophrenia and are associated with genetic variants in enzymes related to proline metabolism

ALDH4A1発現レベルは統合失調症患者の死後脳において上昇し,プロリン代謝関連酵素における遺伝的変異と関連する【JST・京大機械翻訳】

Author (11)： Nagaoka Atsuko (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan) ,  Kunii Yasuto (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan) ,  Kunii Yasuto (Department of Psychiatry, Aizu Medical Center, Fukushima Medical University, 969-3492, Fukushima, Japan) ,  Hino Mizuki (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan) ,  Izumi Ryuta (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan) ,  Nagashima Chisato (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan) ,  Takeshima Akari (Department of Pathology, Brain Research Institute, Niigata University, 951-8585, Niigata, Japan) ,  Sainouchi Makoto (Department of Pathology, Brain Research Institute, Niigata University, 951-8585, Niigata, Japan) ,  Nawa Hiroyuki (Department of Molecular Neurobiology, Brain Research Institute, Niigata University, 951-8585, Niigata, Japan) ,  Kakita Akiyoshi (Department of Pathology, Brain Research Institute, Niigata University, 951-8585, Niigata, Japan) ,  Yabe Hirooki (Department of Neuropsychiatry, School of Medicine, Fukushima Medical University, 960-1295, Fukushima, Japan)
Material： Journal of Psychiatric Research  (J Psychiatr Res)
Volume： 123  Page： 119-127  Publication year： 2020 
JST Material Number： T0194A  ISSN： 0022-3956  CODEN： JPYA3E  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The molecular mechanisms under...

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Thesaurus term： astrocyte ,  drug therapy ,  single nucleotide polymorphism ,  *enzyme ,  ELISA ,  protein ,  prefrontal area ,  genetic variation ,  pathogenesis ,  *schizophrenia ,  aldehyde dehydrogenase ,  allele ,  mitochondria ,  Bipolar Disorder
Semi thesaurus term： manic-depressive psychosis ,  共発現 , 【Automatic Indexing@JST】

JST classification (3)： Mental disorders  (GR03000A) ,  Basic psychiatry  (GR01020I) ,  Genetic variation  (EC01030Y)

Terms in the title (6)： 発現 ,  統合失調症患者 ,  死後脳 ,  リン代謝 ,  酵素 ,  遺伝的変異