Art

J-GLOBAL ID：202002261057795820   Reference number：20A0430177

Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants

新生児および幼児におけるセフェピムの発達集団薬物動態および投与最適化【JST・京大機械翻訳】

Author (10)： Zhao Yang (School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China) ,  Yao Bu-Fan (Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China) ,  Kou Chen (Department of Neonatology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China) ,  Xu Hai-Yan (Department of Neonatology, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, China) ,  Tang Bo-Hao (Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China) ,  Wu Yue-E (Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China) ,  Hao Guo-Xiang (Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China) ,  Zhang Xin-Ping (School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China) ,  Zhao Wei (Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Shandong University, Jinan, China) ,  Zhao Wei (Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Jinan, China)
Material： Frontiers in Pharmacology (Web)
Volume： 11  Page： 14  Publication year： 2020 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Objective: Cefepime is used to...

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Thesaurus term： minimal inhibitory concentration ,  *optimization ,  *neonate ,  pathogen ,  population(ecology) ,  population(statistics) ,  infectious disease ,  software ,  menstruation ,  sensitivity ,  compartment model ,  *baby ,  high performance liquid chromatography ,  simulation ,  lactam ,  oxime ether ,  sulfur heterocyclic compound ,  quaternary ammonium ,  keto acid

Author keywords (5)： cefepime ,  pharmacokinetics ,  infections ,  neonates ,  infants

JST classification (1)： Basic biopharmacy  (GY01021U)

Substance index (1)： Cefepime

Reference (16)：

• Blumer J. L., Reed M. D., Knupp C. (2001). Review of the pharmacokinetics of cefepime in children. Pediatr. Infect. Dis. J. 20 (3), 337-342. doi: doi: 10.1097/00006454-200103000-00032
• B-MS C. (2009). “"Maxipime prescribing information,"” in FDA drug label (Princeton, NJ: BristolMyers Squibb). doi: 10.1097/00006454-200103000-00032
• Capparelli E., Hochwald C., Rasmussen M., Parham A., Bradley J., Moya F. (2005). Population pharmacokinetics of cefepirne in the neonate. Antimicrob. Agents Ch. 49 (7), 2760-2766. doi: doi: 10.1128/Aac.49.7.2760-2766.2005
• Craig W. A. (1998). Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin. Infect. Dis. 26 (1), 1-10; quiz 1-2. doi: doi: 10.1086/516284
• Drusano G. L. (2003). Prevention of resistance: a goal for dose selection for antimicrobial agents. Clin. Infect. Dis. 36, S42-S50. doi: doi: 10.1086/344653

Terms in the title (8)： 新生児 ,  幼児 ,  セフェピム ,  発達 ,  集団 ,  薬物動態 ,  投与 ,  最適化