Art

J-GLOBAL ID：202002264219396326   Reference number：20A0474783

Engineering ApoE3-incorporated biomimetic nanoparticle for efficient vaccine delivery to dendritic cells via macropinocytosis to enhance cancer immunotherapy

癌免疫療法を増強するためのマクロピノサイトーシスによる樹状細胞への効率的ワクチンデリバリーのためのアポE3を組み込んだ生体模倣ナノ粒子のエンジニアリング【JST・京大機械翻訳】

Author (18)： Zhou Songlei (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Zhou Songlei (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Huang Yukun (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Huang Yukun (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Chen Yu (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Chen Yu (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Liu Shanshan (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Liu Shanshan (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Xu Minjun (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Xu Minjun (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Jiang Tianze (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Jiang Tianze (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China) ,  Song Qingxiang (Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, PR China) ,  Jiang Gan (Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, PR China) ,  Gu Xiao (Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, PR China) ,  Gao Xiaoling (Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, PR China) ,  Chen Jun (Shanghai Pudong Hospital & Department of Pharmaceutics, School of Pharmacy,Fudan University, Lane 826, Zhangheng Road, Shanghai, 201203, PR China) ,  Chen Jun (Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, PR China)
Material： Biomaterials
Volume： 235  Page： Null  Publication year： 2020 
JST Material Number： C0964B  ISSN： 0142-9612  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Efficient delivery of vaccines...

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Thesaurus term： receptor ,  lymph node ,  *vaccine ,  antigen ,  endocytosis ,  internalization ,  vaccination ,  subcutaneous administration ,  antigen presentation ,  metastasis ,  *immunotherapy ,  immunological reaction ,  *dendritic cell ,  interferon gamma ,  *nano particle ,  poly(lactic-glycolic acid)

Author keywords (5)： ApoE3 ,  Macropinocytosis ,  Immunotherapy ,  Vaccine ,  Biomimetic

JST classification (2)： Medical materials  (GA05040H) ,  Cell physiology in general  (EF02010S)

Terms in the title (10)： 癌免疫療法 ,  増強 ,  マクロピノサイトーシス ,  樹状細胞 ,  ワクチン ,  デリバリー ,  アポE3 ,  生体模倣 ,  ナノ粒子 ,  エンジニアリング