Art

J-GLOBAL ID：202002264469362265   Reference number：20A0407365

Ubiquitin C-terminal hydrolase-L1 has prognostic relevance and is a therapeutic target for high-grade neuroendocrine lung cancers

ユビキチンC末端ヒドロラーゼ-L1は予後と関連し,高悪性度神経内分泌肺癌の治療標的である

Author (10)： Shimada Yoshihisa (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan) ,  Shimada Yoshihisa (Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, TX, USA) ,  Kudo Yujin (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan) ,  Maehara Sachio (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan) ,  Matsubayashi Jun (Department of Anatomical Pathology, Tokyo Medical University Hospital, Tokyo, Japan) ,  Otaki Yoichi (Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, TX, USA) ,  Kajiwara Naohiro (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan) ,  Ohira Tatsuo (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan) ,  Minna John D. (Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, TX, USA) ,  Ikeda Norihiko (Department of Thoracic Surgery, Tokyo Medical University Hospital, Tokyo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 111  Issue： 2  Page： 610-620  Publication year： 2020 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： tumor cell ,...
Semi thesaurus term： Exosomes ,...

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Author keywords (6)： exosomes ,  extracellular vesicles ,  high-grade neuroendocrine carcinoma ,  large cell neuroendocrine carcinoma ,  small cell lung cancer ,  UCHL1

JST classification (2)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Enzyme in general  (EB09010D)

Terms in the title (7)： ユビキチンC末端ヒドロラーゼ ,  L1 ,  予後 ,  悪性度 ,  神経内分泌 ,  肺癌 ,  治療標的