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J-GLOBAL ID：202002264791939532   Reference number：20A1083922

Systematic Analysis of Targets of Pumilio-Mediated mRNA Decay Reveals that PUM1 Repression by DNA Damage Activates Translesion Synthesis

Pumilio仲介mRNA崩壊の標的の系統的解析はDNA損傷によるPUM1抑制がトランス損傷合成を活性化することを明らかにする【JST・京大機械翻訳】

Author (8)： Yamada Toshimichi (Meiji Pharmaceutical University, Kiyose-shi, Tokyo 204-8588, Japan) ,  Imamachi Naoto (Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Imamura Katsutoshi (Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Taniue Kenzui (Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Kawamura Takeshi (Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan) ,  Suzuki Yutaka (Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa-shi, Chiba 277-8562, Japan) ,  Nagahama Masami (Meiji Pharmaceutical University, Kiyose-shi, Tokyo 204-8588, Japan) ,  Akimitsu Nobuyoshi (Isotope Science Center, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan)
Material： Cell Reports
Volume： 31  Issue： 5  Page： Null  Publication year： 2020 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： RNA-binding proteins (RBPs) pl...

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Thesaurus term： DNA synthesis ,  *RNA ,  *mRNA ,  human ,  cytotoxicity ,  gene expression ,  *DNA lesion ,  Transcriptome ,  RNA binding protein ,  *mRNA decay ,  overexpression ,  mRNA stability ,  RNA sequencing ,  platinum complex ,  antitumor drug ,  ammine complex ,  chloro complex ,  molecular genetic phenomenon
Semi thesaurus term： cisplatin , 【Automatic Indexing@JST】

Author keywords (9)： RNA-binding proteins ,  Pumilio ,  RNA stability ,  RNA-seq ,  RIP-seq ,  BRIC-seq ,  in silico screening ,  DNA damage ,  translesion synthesis

JST classification (4)： Molecular genetics in general  (EC02010J) ,  Biological function  (EB03040U) ,  Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Terms in the title (9)： 仲介 ,  mRNA崩壊 ,  標的 ,  系統 ,  解析 ,  DNA損傷 ,  トランス ,  損傷 ,  活性化