Art

J-GLOBAL ID：202002265738126143   Reference number：20A1681612

Genetic knockout and pharmacologic inhibition of NCX1 attenuate hypoxia-induced pulmonary arterial hypertension

NCX1の遺伝的ノックアウトと薬理学的阻害は低酸素誘発肺動脈高血圧を軽減する【JST・京大機械翻訳】

Author (10)： Nagata Asahi (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Nagata Asahi (Department of General Thoracic, Breast and Pediatric Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Tagashira Hideaki (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Kita Satomi (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Kita Satomi (Department of Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan) ,  Kita Tomo (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Nakajima Naoko (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Abe Kohtaro (Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan) ,  Iwasaki Akinori (Department of General Thoracic, Breast and Pediatric Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Iwamoto Takahiro (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 529  Issue： 3  Page： 793-798  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The Na⁺/Ca<sup>2+<...

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Thesaurus term： heterojunction ,  membrane potential ,  *heredity ,  *oxygen deficiency ,  homeostasis ,  *pulmonary artery ,  *pharmacology ,  up-regulation ,  repeated administration
Semi thesaurus term： 血管平滑筋 ,  輸送体 ,  *NCX1 ,  右心室 ,  肺血管 ,  野生型マウス , 【Automatic Indexing@JST】

Author keywords (5)： Pulmonary arterial hypertension ,  Vascular remodeling ,  Hypoxia ,  Genetic knockout ,  NCX1 inhibitor

JST classification (2)： Vasculature  (EJ04030O) ,  Function of cell components  (EF03060C)

Terms in the title (7)： NCX1 ,  ノックアウト ,  薬理学 ,  阻害 ,  低酸素 ,  誘発 ,  肺動脈高血圧