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J-GLOBAL ID：202002265796215009   Reference number：20A1667233

Involvement of GPR4 in increased growth hormone and prolactin expressions by extracellular acidification in MtT/S cells

MtT/S細胞の細胞外酸性化による成長ホルモンおよびプロラクチン発現増加におけるGPR4の関与

Author (11)： MUSHA Shiori (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  YOSHIDA Saishu (Department of Biochemistry, Jikei University School of Medicine, Tokyo 105-8461, Japan) ,  MURAKAMI Syo (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  KOJIMA Ryotaro (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  DEAI Masahito (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  SASO Naoshi (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  MOGI Chihiro (Laboratory of Integrated Signaling Systems, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan) ,  SATO Koichi (Laboratory of Medical Neuroscience, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan) ,  OKAJIMA Fumikazu (Laboratory of Pathophysiology, Faculty of Pharmacy, Aomori University, Aomori 030-0943, Japan) ,  TOMURA Hideaki (Laboratory of Cell Signaling Regulation, Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan) ,  TOMURA Hideaki (Institute of Endocrinology, Meiji University, Kawasaki 214-8571, Japan)
Material： Journal of Reproduction and Development  (J Reprod Dev)
Volume： 66  Issue： 2  Page： 175-180(J-STAGE)  Publication year： 2020 
JST Material Number： F0766A  ISSN： 0916-8818  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *growth hormone ,...
Semi thesaurus term： *GPR4 ,...

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Author keywords (5)： Extracellular acidification ,  Growth hormone ,  GPR4 ,  MtT/S ,  Prolactin

JST classification (3)： Tumors(=neoplasms)of endocrine system  (GL04000P) ,  Physiology and anatomy of endocrine system  (EJ08000J) ,  Receptors on cell membrane  (EF04030C)

Reference (32)：

• 1. Mehta GU, Lonser RR. Management of hormone-secreting pituitary adenomas. Neuro-oncol 2017; 19: 762-773.
• 2. Jacoby LB, Hedley-Whyte ET, Pulaski K, Seizinger BR, Martuza RL. Clonal origin of pituitary adenomas. J Neurosurg 1990; 73: 731-735.
• 3. Melmed S. Pathogenesis of pituitary tumors. Nat Rev Endocrinol 2011; 7: 257-266.
• 4. Melmed S. Pituitary tumors. Endocrinol Metab Clin North Am 2015; 44: 1-9.
• 5. Kato Y, Ozawa S, Miyamoto C, Maehata Y, Suzuki A, Maeda T, Baba Y. Acidic extracellular microenvironment and cancer. Cancer Cell Int 2013; 13: 89.

Terms in the title (6)： MTT ,  細胞 ,  酸性化 ,  成長ホルモン ,  プロラクチン ,  発現