Art

J-GLOBAL ID：202002266246222488   Reference number：20A0541255

肝・胆・膵がんにおけるMSI検査の位置づけ

Author (3)： OKANO NAOHIRO (杏林大 医 腫瘍内科学) ,  NAGASHIMA FUMIO (杏林大 医 腫瘍内科学) ,  FURUSE JUNJI (杏林大 医 腫瘍内科学)
Material： 月刊腫瘍内科  (腫瘍内科)
Volume： 25  Issue： 2  Page： 219-224  Publication year： Feb. 28, 2020 
JST Material Number： L6395A  ISSN： 1881-6568  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： hepatoma ,...
Semi thesaurus term： FGFR阻害薬 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0541255&from=J-GLOBAL&jstjournalNo=L6395A") }}

JST classification (3)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Molecular genetics in general  (EC02010J)

Substance index (8)： TS-1 ,  Ivosidenib ,  Gemcitabine ,  Sorafenib ,  Fluorouracil ,  Levofolinate calcium ,  E-7080 ,  CPT-11

Reference (20)：

• 日本臨床腫瘍学会.新臨床腫瘍学 改訂第5版.東京:南江堂;2018.pp.12-13.
• Koinuma K, Shitoh K, Miyakura Y, et al. Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas. Int J Cancer 2004 ; 108: 237.
• Goeppert B, Roessler S, Renner M, et al. Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma. Br J Cancer 2019 ; 120: 109.
• Le DT, Durham JN, Smith KN, et al. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science 2017 ; 357: 409.
• Eso Y, Shimizu T, Takeda H, et al. Microsatellite instability and immune checkpoint inhibitors : toward precision medicine against gastrointestinal and hepatobiliary cancers. J Gastroenterol 2019 Sep 7 [Epub ahead of print].

Terms in the title (4)： 肝 ,  膵がん ,  MSI ,  検査