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J-GLOBAL ID：202002266739370644   Reference number：20A0669201

Deregulated Local Protein Synthesis in the Brain Synaptosomes of a Mouse Model for Alzheimer’s Disease

Alzheimer病のマウスモデルの脳シナプトソームにおける脱調節局所蛋白質合成【JST・京大機械翻訳】

Author (16)： Cefaliello Carolina (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Cefaliello Carolina (current address: Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA) ,  Penna Eduardo (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Barbato Carmela (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Di Ruberto Giuseppina (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Mollica Maria Pina (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Trinchese Giovanna (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Cigliano Luisa (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Borsello Tiziana (Department of Pharmacological and Biomolecular Sciences, Milan University, Milan, Italy) ,  Borsello Tiziana (Department of Neuroscience, Mario Negri Institute for Pharmacological Research-IRCCS, Milan, Italy) ,  Chun Jong Tai (Stazione Zoologica Anton Dohrn, Naples, Italy) ,  Giuditta Antonio (Department of Biology, University of Naples Federico II, Naples, Italy) ,  Perrone-Capano Carla (Department of Pharmacy, School of Medicine, University of Naples Federico II, Naples, Italy) ,  Perrone-Capano Carla (Institute of Genetics and Biophysics “Adriano Buzzati Traverso,” CNR, Naples, Italy) ,  Miniaci Maria Concetta (Department of Pharmacy, School of Medicine, University of Naples Federico II, Naples, Italy) ,  Crispino Marianna (Department of Biology, University of Naples Federico II, Naples, Italy)
Material： Molecular Neurobiology
Volume： 57  Issue： 3  Page： 1529-1541  Publication year： 2020 
JST Material Number： W0110A  ISSN： 0893-7648  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: While protein synthe...

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Thesaurus term： dendrite(neuron) ,  inflammation ,  learning ,  human(primates) ,  neuron ,  *protein synthesis ,  *Alzheimer disease ,  *protein ,  *synaptosome ,  synapse ,  electrophoresis ,  pathological state ,  animal
Semi thesaurus term： 過剰発現 ,  シナプス可塑性 , 【Automatic Indexing@JST】

Author keywords (6)： Local protein synthesis ,  Synaptosomes ,  Amyloid precursor protein ,  Alzheimer’s disease ,  Synaptic plasticity ,  Learning

JST classification (2)： Basic neurology  (GN01020W) ,  Central nervous system  (EJ12030F)

Terms in the title (6)： Alzheimer病 ,  マウスモデル ,  脳 ,  シナプトソーム ,  調節 ,  蛋白質合成