Art

J-GLOBAL ID：202002267334589031   Reference number：20A1010631

C-terminal residues of activated protein C light chain contribute to its anticoagulant and cytoprotective activities

活性化プロテインC軽鎖のC末端残基はその抗凝固および細胞保護活性に寄与する【JST・京大機械翻訳】

Author (5)： Yamashita Atsuki (Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA) ,  Zhang Yuqi (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA) ,  Sanner Michel F. (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA) ,  Griffin John H. (Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA) ,  Mosnier Laurent O. (Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA)
Material： Journal of Thrombosis and Haemostasis  (J Thromb Haemost)
Volume： 18  Issue： 5  Page： 1027-1038  Publication year： 2020 
JST Material Number： W1621A  ISSN： 1538-7933  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Activated protein ...

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Thesaurus term： *freezing and solidification ,  interaction ,  blood coagulation ,  receptor ,  Proteins ,  binding site ,  peptide bond hydrolase ,  homeostasis ,  mutagenesis ,  proteolysis ,  *light chain ,  Endothelium ,  cofactor ,  anticoagulant action
Semi thesaurus term： *残基 , 【Automatic Indexing@JST】

Author keywords (5)： activated protein C ,  anticoagulant activity ,  cytoprotective activity ,  protease activated receptor ,  protein S

JST classification (3)： Biological function  (EB03040U) ,  Basic hematology  (GK01020N) ,  Fibrinolysis and blood coagulation  (EJ03040S)

Terms in the title (6)： 活性化プロテインC ,  軽鎖 ,  C末端残基 ,  凝固 ,  細胞保護 ,  活性