Art

J-GLOBAL ID：202002267519889063   Reference number：20A0916867

Plasma screening for the T790M mutation of EGFR and phase 2 study of osimertinib efficacy in plasma T790M-positive non-small cell lung cancer: West Japan Oncology Group 8815L/LPS study

血漿T790M陽性非小細胞肺癌におけるEGFRのT790M突然変異のための血漿スクリーニングと第2相試験:西日本腫瘍学グループ8815L/LPS研究【JST・京大機械翻訳】

Author (23)： Takahama Takayuki (Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Takahama Takayuki (Department of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Azuma Koichi (Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan) ,  Shimokawa Mototsugu (Department of Cancer Information Research, National Kyushu Cancer Center, Fukuoka, Japan) ,  Shimokawa Mototsugu (Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Ube, Japan) ,  Takeda Masayuki (Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Ishii Hidenobu (Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan) ,  Kato Terufumi (Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan) ,  Saito Haruhiro (Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan) ,  Daga Haruko (Department of Medical Oncology, Osaka City General Hospital, Osaka, Japan) ,  Tsuboguchi Yuko (Department of Medical Oncology, Osaka City General Hospital, Osaka, Japan) ,  Okamoto Isamu (Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Otsubo Kohei (Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Akamatsu Hiroaki (Internal Medicine III, Wakayama Medical University, Wakayama, Japan) ,  Teraoka Shunsuke (Internal Medicine III, Wakayama Medical University, Wakayama, Japan) ,  Takahashi Toshiaki (Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto, Japan) ,  Ono Akira (Division of Thoracic Oncology, Shizuoka Cancer Center, Sunto, Japan) ,  Ohira Tatsuo (Department of Surgery, Tokyo Medical University, Shinjuku, Japan) ,  Yokoyama Toshihide (Department of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Japan) ,  Sakai Kazuko (Department of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Yamamoto Nobuyuki (Internal Medicine III, Wakayama Medical University, Wakayama, Japan) ,  Nishio Kazuto (Department of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan) ,  Nakagawa Kazuhiko (Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan)
Material： Cancer (Hoboken, N.J.)
Volume： 126  Issue： 9  Page： 1940-1948  Publication year： 2020 
JST Material Number： D0781B  ISSN： 0008-543X  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Liquid biopsy allo...

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Thesaurus term： droplet ,  *plasma(blood) ,  *tumor ,  *mutation ,  sensitization(photography) ,  percent conversion ,  effectiveness ,  *screening(inspection) ,  *non-small cell lung cancer ,  polymerase chain reaction ,  *EGF receptor ,  *phase 2 study
Semi thesaurus term： 疾患進行 ,  チロシンキナーゼ阻害剤 ,  EGFRチロシンキナーゼ阻害剤 , 【Automatic Indexing@JST】

Author keywords (4)： Cobas EGFR Mutation Test v2 ,  droplet digital polymerase chain reaction (PCR) ,  liquid biopsy ,  osimertinib

JST classification (2)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Terms in the title (11)： 血漿 ,  非小細胞肺癌 ,  EGFR ,  突然変異 ,  スクリーニング ,  第2相試験 ,  西日本 ,  腫瘍学 ,  グループ ,  LPS ,  研究