Art

J-GLOBAL ID：202002268294352755   Reference number：20A0502489

Wenxin Granules Influence the TGFβ-P38/JNK MAPK Signaling Pathway and Attenuate the Collagen Deposition in the Left Ventricle of Myocardial Infarction Rats

Wenxin顆粒はTGFβ-p38/JNK MAPKシグナル伝達経路に影響し,心筋梗塞ラットの左心室におけるコラーゲン沈着を減弱する【JST・京大機械翻訳】

Author (9)： Huang Ya ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Wu Aiming ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Lou Lixia ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Zhang Dongmei ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Nie Bo ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Zhao Yizhou ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Liu Keke ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Zhao Mingjing ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China) ,  Shang Hongcai ( Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Beijing 100700, China)
Material： Cardiology Research and Practice (Web)
Volume： 2019  Page： Null  Publication year： 2019 
JST Material Number： U7690A  ISSN： 2090-8016  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Background. A large number of ...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=20A0502489&from=J-GLOBAL&jstjournalNo=U7690A") }}

Thesaurus term： *myocardial infarction ,  hemodynamics ,  *collagen ,  phosphorylation ,  inflammation ,  *deposition ,  fibrous disease ,  Western blotting ,  cicatrix ,  *TGF beta ,  extracellular matrix ,  *rat ,  *myocardium ,  immunohistochemistry ,  *MAP kinase

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Reference (34)：

• G. A. Roth, C. Johnson, A. Abajobir et al., "Global, regional, and national burden of cardiovascular diseases for 10 causes, 1990 to 2015," Journal of the American College of Cardiology, vol. 70, no. 1, pp. 1-25, 2017.
• S.-B. Ong, S. Hernández-Reséndiz, G. E. Crespo-Avilan et al., "Inflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunities," Pharmacology & Therapeutics, vol. 186, pp. 73-87, 2018.
• N. G. Frangogiannis, "The extracellular matrix in myocardial injury, repair, and remodeling," Journal of Clinical Investigation, vol. 127, no. 5, pp. 1600-1612, 2017.
• S. S. Pattar, A. F. Hassanabad, P. W. M. Fedak, "Acellular extracellular matrix bioscaffolds for cardiac repair and regeneration," Frontiers in Cell and Developmental Biology, vol. 7, pp. 63, 2019.
• Z.-W. Ge, X.-L. Zhu, B.-C. Wang et al., "MicroRNA-26b relieves inflammatory response and myocardial remodeling of mice with myocardial infarction by suppression of MAPK pathway through binding to PTGS2," International Journal of Cardiology, vol. 280, pp. 152-159, 2019.

Terms in the title (12)： 顆粒 ,  TGFβ ,  P38 ,  JNK ,  MAPK ,  シグナル伝達経路 ,  心筋梗塞 ,  ラット ,  左心室 ,  コラーゲン ,  沈着 ,  減弱