Art

J-GLOBAL ID：202002268691232696   Reference number：20A1015711

TREM-2 - p38 MAPK signaling regulates neuroinflammation during chronic cerebral hypoperfusion combined with diabetes mellitus

TREM-2-p38 MAPKシグナル伝達は糖尿病と組み合わせた慢性脳低潅流中の神経炎症を調節する【JST・京大機械翻訳】

Author (9)： Zhang Jiawei (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Liu Yu (Department of Medicine, Shanghai Eighth People’s Hospital, Shanghai, People’s Republic of China) ,  Zheng Yaling (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Luo Yan (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Du Yu (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Zhao Yao (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Guan Jian (Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Zhang Xiaojie (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China) ,  Fu Jianliang (Department of Neurology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China)
Material： Journal of Neuroinflammation (Web)
Volume： 17  Issue： 1  Page： 1-16  Publication year： 2020 
JST Material Number： U7329A  ISSN： 1742-2094  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Diabetes mellitus (DM) and chr...

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Thesaurus term： neuron ,  *inflammation ,  *diabetes mellitus ,  oxygen deficiency ,  pathological state ,  Lentivirus ,  *cellular signal transduction ,  in vitro experiment ,  risk factor ,  microglia ,  hexose ,  aldose
Semi thesaurus term： 認知障害 ,  *P38 ,  炎症反応 ,  過剰発現 , 【Automatic Indexing@JST】

Author keywords (6)： TREM2 ,  p38 MAPK ,  Chronic cerebral hypoperfusion ,  Diabetes ,  Microglia ,  Neuroinflammation

JST classification (2)： Basic neurology  (GN01020W) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： Glucose

Reference (42)：

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• Am J Physiol Heart Circ Physiol; Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment; GA Fulop, S Tarantini, A Yabluchanskiy, A Molnar, CI Prodan, T Kiss, T Csipo, A Lipecz, P Balasubramanian, E Farkas; 316; 2019; H1124-H1140; 10.1152/ajpheart.00776.2018; citation_id=CR2
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• Neurology; Insulin resistance among obese middle-aged is associated with decreased cerebrovascular reactivity; OH Frosch, PL Yau, RS Osorio, H Rusinek, P Storey, A Convit; 89; 2017; 249-255; 10.1212/WNL.0000000000004110; citation_id=CR4
• J Neurosci Res; Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease; MA Daulatzai; 95; 2017; 943-972; 10.1002/jnr.23777; citation_id=CR5

Terms in the title (7)： TREM-2 ,  P38 ,  MAPKシグナル伝達 ,  糖尿病 ,  慢性脳低潅流 ,  神経炎症 ,  調節