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J-GLOBAL ID：202002269542255933   Reference number：20A1200248

Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals

催奇形性化学物質のリスク評価に対するヒト人工多能性幹細胞由来のin vitroでのヒト組織伸長系の応用【JST・京大機械翻訳】

Author (13)： Ninomiya Hiromasa (Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan) ,  Ninomiya Hiromasa (Department of Cell Biology, Nagoya City University, Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan) ,  Intoh Atsushi (Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan) ,  Intoh Atsushi (Voluntary Body for International Health Care in Universities, Nagoya, Japan) ,  Intoh Atsushi (Nara Institute of Science and Technology, Division of Biological Science, Stem Cell Technologies Lab, Takayama-cho, Ikoma 8916-5, Nara, 630-0192, Japan) ,  Ishimine Hisako (Department of Cell Biology and Anatomy, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan) ,  Onuma Yasuko (Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan) ,  Ito Yuzuru (Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan) ,  Michiue Tatsuo (Department of Life Sciences (Biology), Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan) ,  Tazaki Akira (Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan) ,  Tazaki Akira (Voluntary Body for International Health Care in Universities, Nagoya, Japan) ,  Kato Masashi (Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan) ,  Kato Masashi (Voluntary Body for International Health Care in Universities, Nagoya, Japan)
Material： Chemosphere  (Chemosphere. Science for Environmental Technology)
Volume： 250  Page： Null  Publication year： 2020 
JST Material Number： E0843A  ISSN： 0045-6535  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Toxic compounds from the mothe...

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Thesaurus term： food ,  Heredity ,  Placenta ,  Pregnancy ,  human ,  drug therapy ,  morphogenesis ,  Cell Count ,  congenital disease ,  *teratogenicity ,  *in vitro experiment ,  *risk assessment ,  *induced pluripotent stem cell ,  Live Birth ,  organomercury compound

Author keywords (5)： Risk assessment assay ,  Transplacental teratogen ,  Dysmorphic disorders ,  Human pluripotent stem cells ,  Three-dimensional tissue elongation

JST classification (1)： Other pollutants  (SB05040W)

Substance index (1)： Methylmercury

Terms in the title (7)： 催奇形性 ,  化学物質 ,  リスク評価 ,  ヒト ,  人工多能性幹細胞 ,  組織 ,  応用