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J-GLOBAL ID：202002270674547170   Reference number：20A0585630

Three-Component, One-Pot Tandem Sonogashira/Suzuki-Miyaura Coupling Reactions for the Synthesis of a Library of Ceramide-Transport Protein Inhibitors Designed In Silico

in silicoで設計されたセラミド輸送蛋白質阻害剤ライブラリーの合成のための三成分,ワンポット逐次Sonogashira/Suzuki-Miyauraカップリング反応【JST・京大機械翻訳】

Author (5)： Ueno Masaharu (Department of Chemistry School of Science, The University of Tokyo Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan) ,  Ueno Masaharu (Department of Natural Science Graduate School of Advanced Technology and Science, Tokushima University 2-1 Minami-jousanjima, Tokushima, 770-8506, Japan) ,  Miyoshi Norikazu (Department of Natural Science Graduate School of Advanced Technology and Science, Tokushima University 2-1 Minami-jousanjima, Tokushima, 770-8506, Japan) ,  Hanada Kentaro (Department of Biochemistry & Cell Biology, National Institute of Infectious Diseases 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan) ,  Kobayashi Shu (Department of Chemistry School of Science, The University of Tokyo Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan)
Material： Asian Journal of Organic Chemistry
Volume： 9  Issue： 2  Page： 267-273  Publication year： 2020 
JST Material Number： W2500A  ISSN： 2193-5807  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： We have developed a one-pot, t...

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Thesaurus term： palladium catalyst ,  *coupling reaction ,  series connection ,  combinatorial chemistry ,  biological activity ,  Palladium ,  green chemistry ,  C-C bond ,  position isomer ,  *ceramide transport protein ,  *in silico ,  environmental management ,  management ,  environmental conservation

Author keywords (5)： combinatorial chemistry ,  tandem reactions ,  C-C coupling ,  green chemistry ,  palladium

JST classification (1)： Quinolines,isoquinolines  (CF07096H)

Terms in the title (7)： 設計 ,  セラミド輸送蛋白質 ,  阻害剤 ,  ライブラリー ,  ポット ,  逐次 ,  Suzuki-Miyauraカップリング反応