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J-GLOBAL ID：202002270909589617   Reference number：20A1272144

Electropharmacological Characterization of Aciclovir in the Halothane-Anesthetized Dogs: A Proposal of Evaluation Method for Cardiovascular Safety Pharmacology of Anti-virus Drugs

ハロタン麻酔イヌにおけるアシクロビルの電気薬理学的特性化:抗ウイルス薬の心血管安全薬理学の評価法の提案【JST・京大機械翻訳】

Author (12)： Kondo Yoshiki (Department of Pharmacology, Toho University Graduate School of Medicine, Tokyo, Japan) ,  Hagiwara-Nagasawa Mihoko (Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Kambayashi Ryuichi (Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Goto Ai (Department of Pharmacology, Toho University Graduate School of Medicine, Tokyo, Japan) ,  Chiba Koki (Department of Pharmacology, Toho University Graduate School of Medicine, Tokyo, Japan) ,  Nunoi Yoshio (Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Izumi-Nakaseko Hiroko (Department of Pharmacology, Toho University Graduate School of Medicine, Tokyo, Japan) ,  Izumi-Nakaseko Hiroko (Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Matsumoto Akio (Department of Aging Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Sugiyama Atsushi (Department of Pharmacology, Toho University Graduate School of Medicine, Tokyo, Japan) ,  Sugiyama Atsushi (Department of Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan) ,  Sugiyama Atsushi (Department of Aging Pharmacology, Faculty of Medicine, Toho University, Tokyo, Japan)
Material： Cardiovascular Toxicology
Volume： 20  Issue： 4  Page： 419-426  Publication year： 2020 
JST Material Number： W4139A  ISSN： 1559-0259  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Given limited inform...

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Thesaurus term： blood pressure ,  sympathetic nerve system ,  plasma concentration ,  *antiviral drug ,  heart ventricle ,  heartbeat ,  heart atrium ,  *anesthesia ,  pharmacological action ,  bradycardia ,  tachycardia ,  *pharmacology ,  aliphatic chlorine compound ,  aliphatic bromine compound ,  aliphatic fluorine compound
Semi thesaurus term： 再分極 ,  有害事象 , 【Automatic Indexing@JST】

Author keywords (5)： Aciclovir ,  Anti-virus drug ,  Cardiovascular adverse events ,  I_Kr inhibition ,  QT prolongation

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Halothane

Terms in the title (10)： ハロタン ,  麻酔 ,  イヌ ,  アシクロビル ,  薬理学 ,  特性化 ,  抗ウイルス薬 ,  心血管 ,  評価法 ,  提案