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J-GLOBAL ID：202002271295629101   Reference number：20A2573020

NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity

NT5DC2はその触媒活性を調節するチロシンヒドロキシラーゼのりん酸化に影響する【JST・京大機械翻訳】

Author (12)： Nakashima Akira (Department Physiological Chemistry, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Yamaguchi Hisateru (Division of Biomedical Polymer Science, Institute of Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, Japan) ,  Yamaguchi Hisateru (Department of Medical Technology, School of Nursing and Medical Care, Yokkaichi Nursing and Medical Care University, Yokkaichi, Japan) ,  Kondo Mii (Department Physiological Chemistry, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Furumura Takahiro (Department Physiological Chemistry, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Kodani Yu (Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Kaneko Yoko S. (Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Kaneko Yoko S. (Biochemistry and Molecular Cell Biology, Faculty of Pharmacy, Gifu University of Medical Science, Seki, Japan) ,  Kawata Miho (Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Nagasaki Hiroshi (Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Nagatsu Toshiharu (Center for Research Promotion and Support, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan) ,  Ota Akira (Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan)
Material： Journal of Neural Transmission
Volume： 127  Issue： 12  Page： 1631-1640  Publication year： 2020 
JST Material Number： A1107A  ISSN： 0300-9564  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: 5′-Nucleotidase doma...

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Thesaurus term： steric conformation ,  *catalytic activity ,  Amino Acid Sequence ,  Proteins ,  *tyrosine hydroxylase ,  phosphatase ,  *phosphorylation ,  Down-Regulation ,  Western blotting ,  siRNA ,  Genome-Wide Association Study ,  kinase ,  bioassay ,  ketone ,  alicyclic compound ,  fatty acid ,  oxygen heterocyclic compound ,  vinyl compound ,  hydroxy compound ,  tricyclic diterpene ,  carboxylate (ester) ,  catecholamine ,  primary amine ,  amino acid ,  phenolic compound

Author keywords (5)： NT5DC2 ,  DOPA ,  Dopamine ,  Tyrosine hydroxylase ,  Phosphorylation

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (3)： Forskolin ,  Dopamine ,  Tyrosine

Terms in the title (4)： 触媒活性 ,  調節 ,  チロシンヒドロキシラーゼ ,  りん酸化