Art

J-GLOBAL ID：202002271822359252   Reference number：20A0296022

The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer

前立腺癌においてARとMMP9/VEGFシグナル伝達軸の間の機能的リンクはPIP5K1α/PAKTを介して仲介される【JST・京大機械翻訳】

Author (15)： Larsson Per (Division of Experimental Cancer Research, Department of Translational Medicine, Lund University, Clinical Research Centre, Malmo, Sweden) ,  Larsson Per (Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark) ,  Larsson Per (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Syed Khaja Azharuddin Sajid (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Semenas Julius (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Wang Tianyan (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Sarwar Martuza (Division of Experimental Cancer Research, Department of Translational Medicine, Lund University, Clinical Research Centre, Malmo, Sweden) ,  Dizeyi Nishtman (Division of Experimental Cancer Research, Department of Translational Medicine, Lund University, Clinical Research Centre, Malmo, Sweden) ,  Simoulis Athanasios (Department of Clinical Pathology and Cytology, Skane University Hospital, Malmo, Sweden) ,  Hedblom Andreas (Division of Experimental Cancer Research, Department of Translational Medicine, Lund University, Clinical Research Centre, Malmo, Sweden) ,  Hedblom Andreas (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Wai Sun Nyunt (Department of Molecular Biology, Umea University, Umea, Sweden) ,  Odum Niels (Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark) ,  Persson Jenny L. (Division of Experimental Cancer Research, Department of Translational Medicine, Lund University, Clinical Research Centre, Malmo, Sweden) ,  Persson Jenny L. (Department of Molecular Biology, Umea University, Umea, Sweden)
Material： International Journal of Cancer  (IJC)
Volume： 146  Issue： 6  Page： 1686-1699  Publication year： 2020 
JST Material Number： A0267B  ISSN： 0020-7136  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Currently, no effective target...

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Thesaurus term： *cellular signal transduction ,  protein ,  protein complex ,  immersional wetting ,  castration ,  network ,  matrix metalloproteinase ,  androgen receptor ,  interaction ,  *VEGF ,  targeting ,  molecular target therapy ,  *prostatic tumor
Semi thesaurus term： 転移性 ,  *マトリックスメタロプロテイナーゼ9 , 【Automatic Indexing@JST】

Author keywords (6)： matrix metalloproteinases 9 ,  PIP5K1α ,  AKT ,  androgen receptor ,  metastatic prostate cancer ,  targeted therapy

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Basic oncology in general  (GE02010R)

Terms in the title (8)： 前立腺癌 ,  Ar ,  MMP9 ,  VEGF ,  シグナル伝達 ,  リンク ,  pAKT ,  仲介