Art

J-GLOBAL ID：202002273010830222   Reference number：20A2696478

Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling

フラゲリンの細菌外膜小胞仲介サイトゾル送達は宿主NLRC4正準インフラマソームシグナリングを誘発する【JST・京大機械翻訳】

Author (7)： Yang Jungmin (1Department of Microbiology and Immunology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea) ,  Hwang Inhwa (1Department of Microbiology and Immunology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea) ,  Lee Eunju (1Department of Microbiology and Immunology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea) ,  Shin Sung Jae (1Department of Microbiology and Immunology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea) ,  Lee Eun-Jin (2Department of Life Sciences, Korea University, Seoul, South Korea) ,  Rhee Joon Haeng (3Department of Microbiology, Clinical Vaccine R&D Center, Chonnam National University Medical School, Gwangju, South Korea) ,  Yu Je-Wook (1Department of Microbiology and Immunology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea)
Material： Frontiers in Immunology (Web)
Volume： 11  Page： 581165  Publication year： 2020 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Bacteria-released components c...

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Thesaurus term： Escherichia coli ,  flagellum ,  lipopolysaccharide ,  *flagellin ,  Salmonella ,  Salmonella typhimurium ,  Pseudomonas aeruginosa ,  *cytosol ,  endocytosis ,  macrophage ,  cellular signal transduction ,  interleukin 1 ,  caspase ,  natural immunity
Semi thesaurus term： *インフラマソーム , 【Automatic Indexing@JST】

Author keywords (7)： outer membrane vesicles ,  NLRC4 ,  inflammasome ,  interleukin-1 ,  caspase-1 ,  flagellin ,  host defense

JST classification (3)： Biophylaxis and immune systems in general  (ED01010F) ,  Microorganism physiology in general  (EG03051L) ,  Infectious immunity  (ED03030P)

Reference (34)：

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• YuJWLeeMS. Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance. Arch Pharm Res (2016) 39(11):1503-18. doi: doi: 10.1007/s12272-016-0827-4
• BrozP. Recognition of Intracellular Bacteria by Inflammasomes. Microbiol Spectr (2019) 7(2):BAI-0003-2019. doi: doi: 10.1128/microbiolspec.BAI-0003-2019

Terms in the title (9)： フラゲリン ,  細菌 ,  外膜小胞 ,  仲介 ,  サイトゾル ,  送達 ,  宿主 ,  NLRC4 ,  誘発