Art

J-GLOBAL ID：202002273094681683   Reference number：20A0583377

Estrogen Induces Mammary Ductal Dysplasia via the Upregulation of Myc Expression in a DNA-Repair-Deficient Condition

エストロゲンはDNA修復欠損条件におけるMyc発現のアップレギュレーションを介して乳管異形成を誘導する【JST・京大機械翻訳】

Author (13)： Itou Junji (Laboratory of Molecular Life Science, Institute for Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe (FBRI), 2-2 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan) ,  Itou Junji (Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan) ,  Takahashi Rei (Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, 97-1 Kodo, Kyotanabe 610-0395, Japan) ,  Sasanuma Hiroyuki (Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Kyoto 606-8501, Japan) ,  Tsuda Masataka (Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Kyoto 606-8501, Japan) ,  Tsuda Masataka (Program of Mathematical and Life Science, Graduate School of Integrated Sciences for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan) ,  Morimoto Suguru (Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Kyoto 606-8501, Japan) ,  Matsumoto Yoshiaki (Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan) ,  Ishii Tomoko (Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan) ,  Sato Fumiaki (Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan) ,  Sato Fumiaki (Department of Breast Surgery, Kansai Electric Power Hospital & Kansai Electric Power Medical Research Institute, 2-1-7 Fukushima, Fukushima-ku, Osaka 553-0003, Japan) ,  Takeda Shunichi (Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Kyoto 606-8501, Japan) ,  Toi Masakazu (Department of Breast Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan)
Material： iScience
Volume： 23  Issue： 2  Page： Null  Publication year： 2020 
JST Material Number： W5512A  ISSN： 2589-0042  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Mammary ductal dysplasia is a ...

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Thesaurus term： protooncogene ,  mammary gland ,  Molecular Biology ,  female sex hormone ,  precancerous condition ,  Breast ,  breast tumor ,  Cell Biology ,  Cell Proliferation ,  *DNA Repair ,  Phenotype ,  *Up-Regulation ,  prevention ,  *Metaplasia ,  *Myc protein

Author keywords (3)： Molecular Biology ,  Cell Biology ,  Cancer

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S) ,  Carcinogenic mechanisms and factors  (GE02020C)

Terms in the title (9)： エストロゲン ,  DNA修復 ,  欠損 ,  Myc ,  発現 ,  アップレギュレーション ,  乳管 ,  異形成 ,  誘導