Art

J-GLOBAL ID：202002274783238642   Reference number：20A0525106

Structural, functional, and molecular impact on the cardiovascular system in ApoE^-/- mice exposed to aerosol from candidate modified risk tobacco products, Carbon Heated Tobacco Product 1.2 and Tobacco Heating System 2.2, compared with cigarette smoke

たばこの煙と比較した候補修飾リスクタバコ製品,炭素加熱タバコ製品1.2およびタバコ加熱システム2.2からのエアロゾルに曝露されたアポE-/-マウスにおける心血管系に対する構造的,機能的および分子的影響【JST・京大機械翻訳】

Author (15)： Szostak Justyna (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Titz Bjoern (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Schlage Walter K. (Biology Consultant, Max-Baermann-Str. 21, 51429, Bergisch Gladbach, Germany) ,  Guedj Emmanuel (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Sewer Alain (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Phillips Blaine (PMI R&D, Philip Morris International Research Laboratories Pte. Ltd., Science Park II, Singapore) ,  Leroy Patrice (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Buettner Ansgar (Histovia GmbH, Schone Aussicht 5, 51491, Overath, Germany) ,  Neau Laurent (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Trivedi Keyur (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Martin Florian (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Ivanov Nikolai V. (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Vanscheeuwijck Patrick (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Peitsch Manuel C. (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland) ,  Hoeng Julia (PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchatel, Switzerland)
Material： Chemico-Biological Interactions  (Chem Biol Interact)
Volume： 315  Page： Null  Publication year： 2020 
JST Material Number： H0058B  ISSN： 0009-2797  CODEN： CBINA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： To investigate the molecular, ...

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Thesaurus term： thoracic aorta ,  *apo E ,  transcriptome ,  *aerosol(suspended solids) ,  plaque ,  atherosclerosis ,  arteriosclerosis ,  echocardiography ,  immunohistochemistry ,  heart ventricle ,  heart ,  *Nicotiana tabacum ,  *blood vessel ,  cardiovascular system ,  nitrogen heterocyclic compound ,  drug ,  tobacco alkaloid

Author keywords (7)： Ahr ,  ApoE^-/- mice ,  Atherosclerosis ,  Cigarette smoke ,  Candidate modified-risk tobacco products ,  Heart ventricle dysfunction ,  Xenobiotic metabolism

JST classification (2)： Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Substance index (1)： Nicotine

Terms in the title (12)： たばこの煙 ,  修飾 ,  リスク ,  タバコ製品 ,  炭素 ,  タバコ ,  加熱システム ,  エアロゾル ,  曝露 ,  マウス ,  心血管系 ,  分子