Art

J-GLOBAL ID：202002275428181749   Reference number：20A1172763

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold

栄養素誘導親和性スイッチはそのRAG GTPアーゼ-ragulatorリソソーム足場によるmTORC1活性化を制御する【JST・京大機械翻訳】

Author (16)： Lawrence Rosalie E. (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Lawrence Rosalie E. (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Cho Kelvin F. (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Cho Kelvin F. (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Rappold Ronja (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Rappold Ronja (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Thrun Anna (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Thrun Anna (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Tofaute Marie (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Tofaute Marie (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Kim Do Jin (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Moldavski Ofer (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Moldavski Ofer (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA) ,  Hurley James H. (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Zoncu Roberto (Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA) ,  Zoncu Roberto (The Paul F. Glenn Center for Aging Research at the University of California, Berkeley, Berkeley, CA, USA)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 20  Issue： 9  Page： 1052-1063  Publication year： 2018 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: A key step in nutrie...

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Thesaurus term： interface (surface) ,  *nutrient ,  Cytoplasm ,  nucleotide ,  complex (substance) ,  capture ,  *lysosome ,  *GTPase ,  *affinity ,  controlling element ,  *mTORC1 ,  C terminal domain ,  kinase ,  Signal Transduction
Semi thesaurus term： cellular signal transduction ,  不安定化 , 【Automatic Indexing@JST】

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (9)： 栄養素 ,  誘導 ,  親和性 ,  RAG ,  GTPアーゼ ,  リソソーム ,  足場 ,  mTORC1 ,  活性化