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J-GLOBAL ID：202002275451107375   Reference number：20A0214936

Targeting Antibiotic Resistance Genes Is a Better Approach to Block Acquisition of Antibiotic Resistance Than Blocking Conjugal Transfer by Recipient Cells: A Genome-Wide Screening in Escherichia coli

抗生物質耐性遺伝子の標的化は受容体細胞による接合伝達を阻止することより抗生物質耐性の獲得を阻止するためのより良いアプローチである:大腸菌におけるゲノムワイドスクリーニング【JST・京大機械翻訳】

Author (9)： Moriguchi Kazuki (Program of Basic Biology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Japan) ,  Moriguchi Kazuki (Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan) ,  Zoolkefli Fatin Iffah Rasyiqah Mohamad (Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan) ,  Abe Masanobu (Division for Health Service Promotion, University of Tokyo, Tokyo, Japan) ,  Kiyokawa Kazuya (Program of Basic Biology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Japan) ,  Kiyokawa Kazuya (Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan) ,  Yamamoto Shinji (Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan) ,  Suzuki Katsunori (Program of Basic Biology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Japan) ,  Suzuki Katsunori (Department of Biological Science, Graduate School of Science, Hiroshima University, Higashihiroshima, Japan)
Material： Frontiers in Microbiology (Web)
Volume： 10  Page： 2939  Publication year： 2019 
JST Material Number： U7080A  ISSN： 1664-302X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The conjugal transfer is a maj...

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Thesaurus term： conjugation ,  function analysis ,  *screening(inspection) ,  host range ,  *targeting ,  *Escherichia coli ,  survival ratio ,  *genome ,  plasmid ,  *receptor ,  *gene ,  zygote ,  driving force
Semi thesaurus term： *微生物薬物耐性 ,  *接合伝達 , 【Automatic Indexing@JST】

Author keywords (6)： IncP1α-type plasmid ,  spread of antibiotic resistance genes ,  broad host range plasmid ,  conjugal transfer ,  genome-wide screening ,  recipient mutants

JST classification (2)： Microorganism physiology in general  (EG03051L) ,  Physiology and pathogenicity of microbial infection  (EG03053T)

Reference (37)：

• Alalam H., Graf F. E., Palm M., Abadikha M., Zackrisson M., Mattsson M., et al (2018). Conjugation factors controlling F-plasmid antibiotic resistance transmission. bioRxiv [preprint]. doi: 10.1101/271254
• Amábile-Cuevas C. F. (2013). Antibiotic resistance: from darwin to lederberg to keynes. Microb. Drug Resist. 19 73-87. doi: 10.1089/mdr.2012.0115
• Asaduzzaman M. (2018). Antimicrobial resistance: an urgent need for a planetary and ecosystem approach. Lancet Planet. Heal. 2 e99-e100. doi: 10.1016/S2542-5196(18)30019-6
• Bengtsson-Palme J., Boulund F., Fick J., Kristiansson E., Larsson D. G. J. (2014). Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India. Front. Microbiol. 5:648. doi: 10.3389/fmicb.2014.00648
• Beutin L., Achtman M. (1979). Two Escherichia coli chromosomal cistrons, sfrA and sfrB, which are needed for expression of F factor tra functions. J. Bacteriol. 139 730-737. doi: 10.3389/fmicb.2014.00648

Terms in the title (9)： 抗生物質耐性遺伝子 ,  標的化 ,  受容 ,  体細胞 ,  接合伝達 ,  阻止 ,  抗生物質耐性 ,  獲得 ,  大腸菌