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J-GLOBAL ID：202002277399474488   Reference number：20A0976127

Stress-induced microglial activation occurs through β-adrenergic receptor: noradrenaline as a key neurotransmitter in microglial activation

ストレス誘導ミクログリア活性化はβ-アドレナリン受容体を介して起こる:ミクログリア活性化における重要な神経伝達物質としてのノルアドレナリン【JST・京大機械翻訳】

Author (6)： Sugama Shuei (Department of Physiology, Nippon Medical School, Tokyo, Japan) ,  Takenouchi Takato (Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Ibaraki, Japan) ,  Hashimoto Makoto (Division of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Ohata Hisayuki (Department of Physiology, Nippon Medical School, Tokyo, Japan) ,  Takenaka Yasuhiro (Department of Physiology, Nippon Medical School, Tokyo, Japan) ,  Kakinuma Yoshihiko (Department of Physiology, Nippon Medical School, Tokyo, Japan)
Material： Journal of Neuroinflammation (Web)
Volume： 16  Issue： 1  Page： 1-16  Publication year： 2019 
JST Material Number： U7329A  ISSN： 1742-2094  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The involvement of microglia i...

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Thesaurus term： interaction ,  neuron ,  animal ,  Thalamus ,  Hypothalamus ,  nerve fiber ,  *neurotransmitter ,  Eumetopias jubata ,  robustness ,  wild type ,  alpha adrenergic antagonist ,  beta adrenergic antagonist ,  *microglia ,  endocrine gland ,  secretory gland ,  phenol ether ,  polynuclear aromatic compound ,  aminoalcohol ,  secondary amine ,  secondary alcohol ,  nitrogen heterocyclic compound ,  carboline alkaloid ,  carboxylate (ester) ,  hydroxy acid

Author keywords (5)： Microglia ,  Restraint stress ,  Brain ,  CNS ,  Neuroimmunomodulation

JST classification (2)： Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W)

Substance index (2)： Propranolol ,  Yohimbine

Reference (76)：

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• Brain Res Bull; Ultrastructural relations between β-adrenergic receptors and Catecholaminergic neurons; C Aoki, VM Pickel; 29; 1992; 257-263; 10.1016/0361-9230(92)90055-3; citation_id=CR3
• J Neurosci; Sleep loss promotes astrocytic phagocytosis and microglial activation in mouse cerebral cortex; M Bellesi, L Vivo, M Chini, F Gilli, G Tononi, C Cirelli; 37; 2017; 5263-5273; 10.1523/JNEUROSCI.3981-16.2017; citation_id=CR4
• Cell Tissue Res; Locus coeruleus; EE Benarroch; 373; 2017; 221-232; 10.1007/s00441-017-2649-1; citation_id=CR5

Terms in the title (6)： ストレス ,  誘導 ,  ミクログリア活性化 ,  β-アドレナリン受容体 ,  神経伝達物質 ,  ノルアドレナリン