Art

J-GLOBAL ID：202002277462615848   Reference number：20A1740901

Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer’s Disease

ペプチジル-プロリルシス/トランスイソメラーゼPin1とAlzheimer病【JST・京大機械翻訳】

Author (5)： Wang Long (Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China) ,  Zhou Ying (Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China) ,  Zhou Ying (Key Laboratory of Brain Aging and Neurodegenerative Diseases of Fujian Provincial Universities and Colleges, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China) ,  Chen Dongmei (Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China) ,  Lee Tae Ho (Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China)
Material： Frontiers in Cell and Developmental Biology (Web)
Volume： 8  Page： 355  Publication year： 2020 
JST Material Number： U7062A  ISSN： 2296-634X  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Alzheimer’s disease (AD) is th...

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Thesaurus term： aggregation ,  protein ,  phosphorylation ,  biological activity ,  plaque ,  deposition ,  neurofibril ,  *Alzheimer disease ,  cellular signal transduction ,  amino acid ,  nitrogen heterocyclic compound
Semi thesaurus term： 神経変性疾患 ,  動物モデル ,  分子機構 ,  *Pin1 ,  アミロイドβペプチド , 【Automatic Indexing@JST】

Author keywords (5)： Alzheimer’s disease ,  amyloid precursor protein (APP) ,  Pin1 ,  phosphorylation ,  tau

JST classification (3)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Proline

Reference (165)：

• Ahuja P., Cantrelle F. X., Huvent I., Hanoulle X., Lopez J., Smet C., et al (2016). Proline conformation in a functional tau fragment. J. Mol. Biol. 428 79-91. doi: 10.1016/j.jmb.2015.11.023
• Akiyama H., Shin R. W., Uchida C., Kitamoto T., Uchida T. (2005). Pin1 promotes production of Alzheimer’s amyloid beta from beta-cleaved amyloid precursor protein. Biochem. Biophys. Res. Commun. 336 521-529. doi: 10.1016/j.bbrc.2005.08.130
• Albayram O., Angeli P., Bernstein E., Baxley S., Gao Z., Lu K. P., et al (2018). Targeting prion-like cis phosphorylated tau pathology in neurodegenerative diseases. J. Alzheimers Dis. Parkinsonism 8:443. doi: 10.4172/2161-0460.1000443
• Albayram O., Herbert M. K., Kondo A., Tsai C. Y., Baxley S., Lian X., et al (2016). Function and regulation of tau conformations in the development and treatment of traumatic brain injury and neurodegeneration. Cell Biosci. 6:59. doi: 10.1186/s13578-016-0124-4
• Albayram O., Kondo A., Mannix R., Smith C., Tsai C. Y., Li C., et al (2017). Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae. Nat. Commun. 8:1000. doi: 10.1038/s41467-017-01068-4

Terms in the title (4)： トランス ,  イソメラーゼ ,  Pin1 ,  Alzheimer病