Art

J-GLOBAL ID：202002279411480720   Reference number：20A1198290

Astaxanthin improves osteopenia caused by aldehyde-stress resulting from Aldh2 mutation due to impaired osteoblastogenesis

アスタキサンチンは骨芽細胞腫形成障害によるALDH2突然変異に起因するアルデヒドストレスによって引き起こされる骨減少症を改善する【JST・京大機械翻訳】

Author (7)： Hoshi Hiroko (Department of Biotechnology, Maebashi Institute of Technology, 460-1 Kamisadori-machi, Maebashi-shi, Gumma, 371-0816, Japan) ,  Hoshi Hiroko (Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo, 160-8582, Japan) ,  Monoe Fuka (Department of Biotechnology, Maebashi Institute of Technology, 460-1 Kamisadori-machi, Maebashi-shi, Gumma, 371-0816, Japan) ,  Ohsawa Ikuroh (Biological Process of Aging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi, Tokyo, 173-0015, Japan) ,  Ohta Shigeo (Department of Neurology Medicine, Juntendo University Graduate School of Medicine, 2-1-1 Bunkyo-ku, Tokyo, 113-8431, Japan) ,  Miyamoto Takeshi (Department of Orthopedic Surgery, Keio University School of Medicine, 35 Shinano-machi, Shinjuku-ku, Tokyo, 160-8582, Japan) ,  Miyamoto Takeshi (Department of Orthopaedic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 527  Issue： 1  Page： 270-275  Publication year： 2020 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Aldehyde dehydrogenase 2 (ALDH...

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Thesaurus term： amino acid ,  *aldehyde ,  osteogenesis ,  Bone Marrow ,  Proteins ,  *Mutation ,  metabolic error ,  femur ,  osteoporosis ,  transgenic mouse ,  *osteoblast ,  Bone Density ,  mesenchymal cell ,  Cell Survival ,  bone of leg ,  aliphatic aldehyde

Author keywords (5)： Astaxanthin ,  ALDH2 ,  Osteopenia ,  Osteoblast ,  Acetaldehyde

JST classification (2)： Skeletal system  (EJ10030R) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Acetaldehyde

Terms in the title (7)： アスタキサンチン ,  骨芽細胞腫 ,  障害 ,  ALDH2 ,  突然変異 ,  起因 ,  骨減少症