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J-GLOBAL ID：202002280917732784   Reference number：20A2480529

Increased expression of hras induces early, but not full, senescence in the immortal fish cell line, EPC

hrasの発現増加は不死化魚類細胞系EPCにおいて初期ではなく初期老化を誘導する【JST・京大機械翻訳】

Author (5)： Futami Kunihiko (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Aoyama Kako (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Fukuda Kazuki (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Maita Masashi (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Katagiri Takayuki (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan)
Material： Gene  (International Journal Focusting on Gene Cloning and Gene Structure and Function)
Volume： 765  Page： Null  Publication year： 2021 
JST Material Number： E0701B  ISSN： 0378-1119  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In contrast to most mammals in...

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Thesaurus term： gene ,  human(primates) ,  phenotype ,  Mammalia ,  *senile change ,  cultured cell ,  telomere ,  in vitro experiment ,  beta-galactosidase ,  Ras protein ,  p53 protein ,  cell aging
Semi thesaurus term： *細胞株 ,  過剰発現 ,  形態特性 , 【Automatic Indexing@JST】

Author keywords (5)： Ras ,  Ras-induced senescence ,  SASP ,  Senescence-like growth arrest ,  EPC

JST classification (4)： Cell components in general  (EF03010Z) ,  Function of cell components  (EF03060C) ,  Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Terms in the title (8)： 発現 ,  不死化 ,  魚類 ,  細胞系 ,  EPC ,  初期 ,  老化 ,  誘導