Art

J-GLOBAL ID：202002281167284947   Reference number：20A2359057

Regulation of metabolic homeostasis through nutritional sensing by epigenome.

エピゲノムを介した栄養センシングと代謝恒常性の維持・調節

Author (4)： ARAKI HIROTAKA (熊本大 発生医研 細胞医学分野) ,  ARAKI HIROTAKA (熊本大 大学院生命科学研究部 代謝内科) ,  HINO SHINJIRO (熊本大 発生医研 細胞医学分野) ,  NAKAO MITSUYOSHI (熊本大 発生医研 細胞医学分野)
Material： 月刊糖尿病・内分泌代謝科  (Diabetology, Endocrinology & Metabolology)
Volume： 51  Issue： 4  Page： 315-322  Publication year： Oct. 28, 2020 
JST Material Number： L3890A  ISSN： 2435-1946  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *genetic regulation ,...
Semi thesaurus term： *エピゲノム制御 ,...

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JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Reference (18)：

• Ravelli AC, Meulen JH, Osmond C, et al. Obesity at the Age of 50 Y in Men and Women Exposed to Famine Prenatally. Am J Clin Nutr 1999 ; 70 : 811.
• Park JH, Stoffers DA, Nicholls RD, Simmons RA. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest 2008 ; 118 : 2316.
• Suter MA, Chen A, Burdine MS, et al. A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J 2012 ; 26 : 5106.
• DiTroia SP, Percharde M, Guerquin MJ, et al. Maternal vitamin C regulates reprogramming of DNA methylation and germline development. Nature 2019 ; 573 : 271.
• Wellen KE, Hatzivassiliou G, Sachdeva UM, et al. ATP-citrate lyase links cellular metabolism to histone acetylation. Science 2009 ; 324 : 1076.

Terms in the title (6)： エピゲノム ,  栄養 ,  センシング ,  代謝 ,  恒常性 ,  調節