Art

J-GLOBAL ID：202002281684728837   Reference number：20A2453885

Thrombomodulin ameliorates transforming growth factor-β1-mediated chronic kidney disease via the G-protein coupled receptor 15/Akt signal pathway

トロンボモジュリンはG蛋白質共役受容体15/Aktシグナル経路を介して形質転換成長因子β1仲介慢性腎臓病を改善する【JST・京大機械翻訳】

Author (20)： Takeshita Atsuro (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Takeshita Atsuro (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Yasuma Taro (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Yasuma Taro (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Nishihama Kota (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  D'Alessandro-Gabazza Corina N. (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Toda Masaaki (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Totoki Toshiaki (Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Okano Yuko (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Okano Yuko (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Uchida Akihiro (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Inoue Ryo (Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki, Kanawaga, Japan) ,  Qin Liqiang (Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Lihai, Zhejiang Province, People’s Republic of China) ,  Wang Shujie (Department of Neural Regeneration and Cell Communication, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  D'Alessandro Valeria Fridman (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Kobayashi Tetsu (Department of Pulmonary and Critical Care Medicine, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Takei Yoshiyuki (Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Mizoguchi Akira (Department of Neural Regeneration and Cell Communication, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Yano Yutaka (Department of Diabetes, Metabolism, and Endocrinology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan) ,  Gabazza Esteban C. (Department of Immunology, Mie University Graduate School of Medicine, Tsu-city, Mie, Japan)
Material： Kidney International  (Kidney Int)
Volume： 98  Issue： 5  Page： 1179-1192  Publication year： 2020 
JST Material Number： E0559B  ISSN： 0085-2538  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Kidney fibrosis is the common ...

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Thesaurus term： interaction ,  Glomerulus ,  human ,  *kidney disease ,  *TGF ,  mesenchyme ,  fibrous disease ,  transgenic mouse ,  Apoptosis ,  pathogenesis ,  *Thrombomodulin ,  *Chronic kidney disease ,  podocyte ,  *membrane glycoprotein ,  *transmembrane protein
Semi thesaurus term： 腎線維症 ,  臓器障害 ,  足細胞 , 【Automatic Indexing@JST】

Author keywords (5)： apoptosis ,  chronic kidney disease ,  G-protein coupled receptor ,  recombinant human thrombomodulin ,  transforming growth factor-β1

JST classification (1)： Basic medicine on urogenital system  (GM01020T)

Terms in the title (7)： トロンボモジュリン ,  G蛋白質共役受容体 ,  Akt ,  シグナル経路 ,  形質転換成長因子β1 ,  仲介 ,  慢性腎臓病