Art

J-GLOBAL ID：202002282486121562   Reference number：20A0805898

Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts

活性化癌関連線維芽細胞から抽出されたサイトカインの抑制を介して肝内胆管癌の攻撃性を阻害するNintedanib【JST・京大機械翻訳】

Author (18)： Yamanaka Takahiro (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Harimoto Norifumi (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Yokobori Takehiko (Gunma University Initiative for Advanced Research (GIAR), Gunma, Japan) ,  Muranushi Ryo (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Hoshino Kouki (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Hagiwara Kei (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Gantumur Dolgormaa (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Handa Tadashi (Department of Diagnostic Pathology, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Handa Tadashi (Department of Social Welfare, Gunma University of Health and Welfare, Gunma, Japan) ,  Ishii Norihiro (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Tsukagoshi Mariko (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Tsukagoshi Mariko (Department of Innovative Cancer Immunotherapy, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Igarashi Takamichi (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Tanaka Hiroshi (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Watanabe Akira (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Kubo Norio (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Araki Kenichiro (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan) ,  Shirabe Ken (Department of General Surgical Science, Division of Hepatobiliary and Pancreatic Surgery, Gunma University, Graduate School of Medicine, Gunma, Japan)
Material： British Journal of Cancer
Volume： 122  Issue： 7  Page： 986-994  Publication year： 2020 
JST Material Number： C0922B  ISSN： 0007-0920  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Background: Intrahe...

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Thesaurus term： in vitro experiment ,  combination therapy ,  *fibroblast ,  interleukin ,  therapeutic planning ,  heterotrans plantation ,  targeting ,  cytotoxicity ,  interleukin 8 ,  *cytokine ,  hepatic fibrosis ,  alpha SMA ,  halogeno sugar ,  deoxyribonucleoside
Semi thesaurus term： 腫瘍成長 ,  悪性腫瘍 , 【Automatic Indexing@JST】

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (1)： Gemcitabine

Terms in the title (6)： 活性化 ,  癌関連線維芽細胞 ,  サイトカイン ,  肝内胆管癌 ,  攻撃性 ,  阻害