Art

J-GLOBAL ID：202002282648569577   Reference number：20A0027310

SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability

PIAS1によるSUMO3修飾はアンドロゲン受容体細胞分布と安定性を調節する【JST・京大機械翻訳】

Author (13)： Yang Nanyang (The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, People’s Republic of China) ,  Yang Nanyang (Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Institute of Cytology and Genetics, Hengyang School of Medicine, University of South China, Hengyang, People’s Republic of China) ,  Liu Sitong (The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, People’s Republic of China) ,  Liu Sitong (College of Life Sciences, Jilin University, Changchun, People’s Republic of China) ,  Qin Tian (The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, People’s Republic of China) ,  Liu Xintong (Dental Hospital, Jilin University, Changchun, China) ,  Liu Xintong (Bioprobe Application Research Unit, RIKEN-Max Planck Joint Research Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan) ,  Liu Xintong (Graduate School of Medical & Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Watanabe Nobumoto (Bioprobe Application Research Unit, RIKEN-Max Planck Joint Research Division, RIKEN Center for Sustainable Resource Science, Saitama, Japan) ,  Watanabe Nobumoto (Graduate School of Medical & Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan) ,  Mayo Kevin H. (Biochemistry, Molecular Biology, and Biophysics, Health Sciences Center, University of Minnesota, Minneapolis, USA) ,  Li Jiang (Dental Hospital, Jilin University, Changchun, China) ,  Li Xiaomeng (The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun, People’s Republic of China)
Material： Cell Communication and Signaling (Web)
Volume： 17  Issue： 1  Page： 1-16  Publication year： 2019 
JST Material Number： U7050A  ISSN： 1478-811X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Abnormal reactivation of andro...

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Thesaurus term： proteasome ,  ubiquitination ,  conjugation(metabolism) ,  ligase ,  cytosol ,  immunostaining ,  crosstalk(interaction) ,  translocation(genetics) ,  *androgen receptor ,  interaction ,  ubiquitin ,  down-regulation ,  *receptor ,  prostatic tumor ,  complex(substance)

Author keywords (3)： Sumoylation PIAS1 ,  SUMO3 ,  Androgen receptor

JST classification (3)： Cell physiology in general  (EF02010S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Gene expression  (EC02040Q)

Reference (50)：

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• Curr Opin Oncol; The androgen/androgen receptor axis in prostate cancer; EG Bluemn, PS Nelson; 24; 3; 2012; 251-257; 10.1097/CCO.0b013e32835105b3; citation_id=CR4
• Endocr Connect; Clinical relevance of androgen receptor alterations in prostate cancer; E Jernberg, A Bergh, P Wikstrom; 6; 8; 2017; R146-RR61; 10.1530/EC-17-0118; citation_id=CR5

Terms in the title (7)： PIAS1 ,  SUMO3 ,  修飾 ,  アンドロゲン受容体 ,  細胞分布 ,  安定性 ,  調節