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J-GLOBAL ID：202002283273288446   Reference number：20A0508509

Visualization of AMPA receptors in living human brain with positron emission tomography

AMPA受容体/PET画像可視化:ヒト生体脳中のAMPA受容体の陽電子放出断層撮影による可視化

Author (37)： MIYAZAKI Tomoyuki (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  NAKAJIMA Waki (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  HATANO Mai (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SHIBATA Yusuke (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  KUROKI Yoko (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  ARISAWA Tetsu (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SERIZAWA Asami (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SANO Akane (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  KOGAMI Sayaka (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  YAMANOUE Tomomi (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  KIMURA Kimito (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  HIRATA Yushi (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  TAKADA Yuuki (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  TAKAHASHI Takuya (Dep. of Physiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  ISHIWATA Yoshinobu (Dep. of Radiology, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  SONODA Masaki (Dep. of Neurosurgery, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  IKEGAYA Naoki (Dep. of Neurosurgery, Yokohama City Univ. Graduate School of Medicine, Yokohama, JPN) ,  TOKUNAGA Masaki (Dep. of Functional Brain Imaging Res., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  SEKI Chie (Dep. of Functional Brain Imaging Res., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  NAGAI Yuji (Dep. of Functional Brain Imaging Res., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  MINAMIMOTO Takafumi (Dep. of Functional Brain Imaging Res., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  HIGUCHI Makoto (Dep. of Functional Brain Imaging Res., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  KAWAMURA Kazunori (Dep. of Radiopharmaceuticals Dev., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  ZHANG Ming-Rong (Dep. of Radiopharmaceuticals Dev., National Inst. of Radiological Sci., National Inst. for Quantum and Radiological Sci. and Technol., Chiba, JPN) ,  IWASAKI Masaki (Dep. of Neurosurgery, National Center Hospital of Neurology and Psychiatry, Kodaira, JPN) ,  KUNII Naoto (Dep. of Neurosurgery, Univ. Tokyo Graduate School of Medicine, Tokyo, JPN) ,  KIMURA Yuichi (Fac. of Biology-Oriented Sci. and Technol., Kindai Univ., Kinokawa, JPN) ,  YAMASHITA Fumio (Div. of Ultrahigh-Field-Strength MRI, Inst. for Biomedical Sci., Iwate Medical Univ., Yahaba, JPN) ,  TAGURI Masataka (Dep. of Data Sci., Yokohama City Univ. School of Data Sci., Yokohama, JPN) ,  TANI Hideaki (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  NAGAI Nobuhiro (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  KOIZUMI Teruki (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  NAKAJIMA Shinichiro (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  MIMURA Masaru (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  UCHIDA Hiroyuki (Dep. of Neuropsychiatry, Keio Univ. School of Medicine, Tokyo, JPN) ,  YUZAKI Michisuke (Dep. of Physiology, Keio Univ. School of Medicine, Tokyo, JPN) ,  KATO Hiroki (Dep. of Nuclear Medicine and Tracer Kinetics, Osaka Univ. Graduate School of Medicine, Osaka, JPN)
Material： Nature Medicine  (Nat Med)
Volume： 26  Issue： 2  Page： 281-288  Publication year： Feb. 2020 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： epilepsy ,  evaluation criterion ,  *PET(tomography) ,  glutamate receptor ,  protein ,  *AMPA receptor ,  *visualization ,  phase 2 study ,  *human(primates) ,  clinical trial ,  connectivity
Semi thesaurus term： 内側側頭葉てんかん ,  有害事象 ,  精神神経疾患 ,  *PET画像 , 【Automatic Indexing@JST】

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (7)： AMPA受容体 ,  PET画像 ,  可視化 ,  ヒト ,  生体 ,  脳 ,  陽電子放出断層撮影