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J-GLOBAL ID：202002283989603099   Reference number：20A2249659

Evaluation of the pharmacokinetics of 2-carba-cyclic phosphatidic acid by liquid chromatography-triple quadrupole mass spectrometry

液体クロマトグラフィー-三重四重極質量分析による2-カルバ-環状ホスファチジン酸の薬物動態の評価【JST・京大機械翻訳】

Author (12)： Shimizu Yoshibumi (Ochadai Academic Production, Ochanomizu University, Tokyo, Japan) ,  Fukasawa Keiko (Ochadai Academic Production, Ochanomizu University, Tokyo, Japan) ,  Yamamoto Shinji (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan) ,  Shibaike Yuki (Institute for Human Life Innovation, Ochanomizu University, Tokyo, Japan) ,  Shibaike Yuki (Research Organization for the Promotion of Global Women’s Leadership, Ochanomizu University, Tokyo, Japan) ,  Tsukahara Ryoko (Ochadai Academic Production, Ochanomizu University, Tokyo, Japan) ,  Ishikawa Masaki (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan) ,  Iwasa Kensuke (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan) ,  Yoshikawa Keisuke (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Saitama, Japan) ,  Gotoh Mari (Ochadai Academic Production, Ochanomizu University, Tokyo, Japan) ,  Gotoh Mari (Institute for Human Life Innovation, Ochanomizu University, Tokyo, Japan) ,  Murakami-Murofushi Kimiko (Ochadai Academic Production, Ochanomizu University, Tokyo, Japan)
Material： Prostaglandins & Other Lipid Mediators  (Prostaglandins and Other Lipid Mediators)
Volume： 150  Page： Null  Publication year： 2020 
JST Material Number： B0434C  ISSN： 1098-8823  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cyclic phosphatidic acid (cPA)...

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Thesaurus term： mass spectrometry ,  Half-Life ,  Plasma ,  *liquid chromatography ,  plasma concentration ,  intraperitoneal administration ,  Rattus ,  ischemia ,  metastasis ,  osteoarthrosis ,  peritoneal cavity ,  Multiple Sclerosis ,  therapeutic planning ,  *quadrupole mass spectrometry ,  lysophosphatidic acid ,  Myomorpha

Author keywords (4)： 2ccPA ,  Enterosoluble capsule ,  Oral administration ,  Mass spectrometry

JST classification (5)： Biological function  (EB05020M) ,  Basic research of anti-inflammatory drugs  (GW15010T) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Miscellaneous analytical methods of organic compounds  (CC08034J) ,  Basic biopharmacy  (GY01021U)

Terms in the title (6)： 液体クロマトグラフィー ,  三重 ,  四重極質量分析 ,  環状ホスファチジン酸 ,  薬物動態 ,  評価