Art

J-GLOBAL ID：202002284594410267   Reference number：20A0501327

Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice

閉経後うつ病モデルマウスにおけるHippocampusにおける5-HT1A受容体およびPKA-CREB-BDNFシグナル伝達による加味is散の抗うつ効果【JST・京大機械翻訳】

Author (6)： Shimizu Shoko ( Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan) ,  Ishino Yugo ( Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan) ,  Takeda Takashi ( Division of Women Medicine, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan) ,  Tohyama Masaya ( Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan) ,  Tohyama Masaya ( Osaka Prefectural Hospital Organization, Osaka, Osaka 541-8567, Japan) ,  Miyata Shingo ( Division of Molecular Brain Science, Research Institute of Traditional Asian Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan)
Material： Evidence-Based Complementary and Alternative Medicine (Web)
Volume： 2019  Page： Null  Publication year： 2019 
JST Material Number： U7703A  ISSN： 1741-427X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Females are well known to suff...

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Thesaurus term： *depression (symptom) ,  adrenal gland ,  *CRE binding protein ,  phosphorylation ,  *depression (disease) ,  Chinese drug ,  mental manifestation ,  *receptor ,  repeated administration ,  Hypothalamus ,  Eumetopias jubata ,  Ovariectomy ,  Serum ,  *Signal Transduction ,  endocrine gland ,  secretory gland
Semi thesaurus term： *BDNF ,  *cellular signal transduction , 【Automatic Indexing@JST】

JST classification (3)： Central nervous system  (EJ12030F) ,  Mental disorders  (GR03000A) ,  Basic psychiatry  (GR01020I)

Reference (67)：

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• WHO, Depression and Other Common Mental Disorders: Global Health Estimates, World Health Organization, Geneva, Switzerland, 2017.
• S. J. Lupien, B. S. McEwen, M. R. Gunnar, C. Heim, "Effects of stress throughout the lifespan on the brain, behaviour and cognition," Nature Reviews Neuroscience, vol. 10, no. 6, pp. 434-445, 2009.
• P. Llaneza, M. P. García-Portilla, D. Llaneza-Suárez, B. Armott, F. R. Pérez-López, "Depressive disorders and the menopause transition," Maturitas, vol. 71, no. 2, pp. 120-130, 2012.
• C. N. Soares, "Depression and menopause," Psychiatric Clinics of North America, vol. 40, no. 2, pp. 239-254, 2017.

Terms in the title (10)： 閉経後うつ病 ,  モデルマウス ,  Hippocampus ,  5-HT1A受容体 ,  pKa ,  CREB ,  BDNF ,  シグナル伝達 ,  IS ,  うつ