Art
J-GLOBAL ID：202002284705115955   Reference number：20A2656828

Structural basis for producing selective MAP2K7 inhibitors

選択的MAP2K7阻害剤を生産するための構造的基礎【JST・京大機械翻訳】
Author (5)：
Murakawa Yuka

About Murakawa Yuka

(Graduate School of Science, Osaka Prefecture University, Osaka 599-8531, Japan)

About Graduate School of Science, Osaka Prefecture University, Osaka 599-8531, Japan

, 
Valter Shirly

About Valter Shirly

(Whol Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel)

About Whol Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel

, 
Barr Haim

About Barr Haim

(Whol Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel)

About Whol Institute for Drug Discovery of the Nancy and Stephen Grand Israel National Center for Personalized Medicine, The Weizmann Institute of Science, Rehovot 7610001, Israel

, 
London Nir

About London Nir

(Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel)

About Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel

, 
Kinoshita Takayoshi

About Kinoshita Takayoshi

(Graduate School of Science, Osaka Prefecture University, Osaka 599-8531, Japan)

About Graduate School of Science, Osaka Prefecture University, Osaka 599-8531, Japan


Material：
Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)

About Bioorganic & Medicinal Chemistry Letters


Volume： 30  Issue： 22  Page： Null  Publication year： 2020 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
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Mitogen-activated protein kina...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
crystal structure

About crystal structure

, 
complex(substance)

About complex(substance)

, 
covalent bond

About covalent bond

, 
*electrophilic reagent

About electrophilic reagent

, 
MAP kinase kinase

About MAP kinase kinase

, 
aliphatic carboxylic acid

About aliphatic carboxylic acid

, 
carboxamide

About carboxamide

, 
vinyl compound

About vinyl compound

, 
unsaturated carboxylic acid

About unsaturated carboxylic acid


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
創薬

About 創薬

, 
キナーゼ

About キナーゼ

, 
創薬標的

About 創薬標的

, 【Automatic Indexing@JST】
Author keywords (4)：
MAP2K7

About MAP2K7

, 
Covalent bonding inhibitor

About Covalent bonding inhibitor

, 
Structural flexibility

About Structural flexibility

, 
Selectivity

About Selectivity

JST classification (2)：
JST classification
Category name(code) classified by JST.
Enzyme in general 
(EB09010D)

About Enzyme in general

,  Basic research of enzyme preparations and enzyme inhibitor preparations 
(GW21010W)

About Basic research of enzyme preparations and enzyme inhibitor preparations

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Acrylamide

About Acrylamide

Terms in the title (2)：
Terms in the title
Keywords automatically extracted from the title.
阻害剤

About 阻害剤

, 
基礎

About 基礎


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