Art

J-GLOBAL ID：202002284719058278   Reference number：20A2804343

Liver (Liver - Adipose Tissue Crosstalk)

2.肝臓(肝臓-脂肪組織間クロストーク)

Author (2)： TSUJIMOTO KAZUTAKA (東京医科歯科大学大学院分子内分泌代謝学分野(糖尿病・内分泌・代謝内科)) ,  YAMADA TETSUYA (東京医科歯科大学大学院分子内分泌代謝学分野(糖尿病・内分泌・代謝内科))
Material： 糖尿病(Web)  (Journal of the Japan Diabetes Society (Web))
Volume： 63  Issue： 9  Page： 594-597(J-STAGE)  Publication year： Sep. 30, 2020 
JST Material Number： U0674A  ISSN： 1881-588X  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： Type 2 diabetes mellitus ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (2)： Basic medicine on digestive system  (GH01020E) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： Pioglitazone

Reference (15)：

• 1) Rebollo A, Roglans N, Baena M, Padrosa A, Sánchez R, Merlos M, Alegret M, Laguna J (2014) Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats. J Nutr Biochem 25: 250-258
• 2) Wei Y, Pagliassotti M (2004) Hepatospecific effects of fructose on c-jun NH2-terminal kinase: Implications for hepatic insulin resistance. Am J Physiol Endocrinol Metab 287: E926-E933
• 3) Price NL, Gomes A, Ling A, Duarte F, Martin-Montalvo A, North B, Agarwal B, Ye L, Ramadori G, Teodoro J, Hubbard B, Varela A, Davis J, Varamini B, Hafner A, Moaddel R, Rolo A, Coppari R, Palmeira C, Cabo R, Baur J, Sinclair D (2012) SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab 15: 675-690
• 4) Chan SM, Sun R, Zeng X, Choong Z, Wang H, Watt M, Ye J (2013) Activation of PPARalpha ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress. Diabetes 62: 2095-2105
• 5) Balakumar M, Raji L, Prabhu D, Sathishkumar C, Prabu P, Mohan V, Balasubramanyam M (2016) High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress. Mol Cell Biochem 423: 93-104

Terms in the title (3)： 肝臓 ,  脂肪組織 ,  クロストーク