Art

J-GLOBAL ID：202002285808132302   Reference number：20A0797403

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

CREBHはFGF21依存性およびFGF21非依存性機構により食事誘発性肥満,インスリン抵抗性および代謝障害を改善する【JST・京大機械翻訳】

Author (21)： Satoh Aoi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Han Song-iee (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Han Song-iee (International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Araki Masaya (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Nakagawa Yoshimi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Nakagawa Yoshimi (International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Ohno Hiroshi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Mizunoe Yuhei (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Kumagai Kae (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Murayama Yuki (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Osaki Yoshinori (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Iwasaki Hitoshi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Sekiya Motohiro (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Konishi Morichika (Laboratory of Microbial Chemistry, Kobe Pharmaceutical University, 4-19-1, Motoyamakitamachi, Higashinada-Ku, Kobe, Hyogo, 658-8558, Japan) ,  Itoh Nobuyuki (Department of Genetic Biochemistry, Graduate School of Pharmaceutical Science, Kyoto University, 46-29 Yoshida-Shimoadachi-Cho, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan) ,  Matsuzaka Takashi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Sone Hirohito (Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, 757 Asahimachi, Niigata, Niigata 951-8510, Japan) ,  Shimano Hitoshi (Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Shimano Hitoshi (International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Shimano Hitoshi (Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan) ,  Shimano Hitoshi (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology (AMED-CREST), 1-7-1 Otemachi, Chiyoda-ku, Tokyo, Japan)
Material： iScience
Volume： 23  Issue： 3  Page： Null  Publication year： 2020 
JST Material Number： W5512A  ISSN： 2589-0042  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Mice overexpressing the nuclea...

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Thesaurus term： Plasma ,  Energy Metabolism ,  Inflammation ,  hormone ,  *Obesity ,  *metabolic error ,  browning ,  Karyotype ,  FGF ,  *Insulin resistance ,  glucose metabolism ,  Adipose Tissue, White ,  *FGF21 ,  overexpression ,  groin
Semi thesaurus term： groin , 【Automatic Indexing@JST】

Author keywords (2)： Obesity Medicine ,  Molecular Genetics

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Metabolism and nutrition of lipids  (EJ02034Q)

Terms in the title (7)： FGF21 ,  依存性 ,  非依存性 ,  食事 ,  肥満 ,  インスリン抵抗性 ,  代謝障害