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J-GLOBAL ID：202002287236527851   Reference number：20A0590962

The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside

Escherichia coli alkA遺伝子は酸化されたdeoxynucleシドによる変異誘発を緩和するために活性化される【JST・京大機械翻訳】

Author (16)： Grosvik Kristin (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Tesfahun Almaz Nigatu (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Muruzabal-Lecumberri Izaskun (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Haugland Gyri Teien (Department of Biological Sciences, University of Bergen, Bergen, Norway) ,  Leiros Ingar (The Norwegian Structural Biology Centre, Department of Chemistry, UiT - The Arctic University of Norway, Tromso, Norway) ,  Ruoff Peter (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Kvaloy Jan Terje (Department of Mathematics and Physics, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Knaevelsrud Ingeborg (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  .ANGS.nensen Hilde (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Alexeeva Marina (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway) ,  Sato Kousuke (Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Tobetsu, Japan) ,  Matsuda Akira (Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan) ,  Alseth Ingrun (Department of Microbiology, Oslo University Hospital, Oslo, Norway) ,  Klungland Arne (Department of Microbiology, Oslo University Hospital, Oslo, Norway) ,  Klungland Arne (Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway) ,  Bjelland Svein (Department of Chemistry, Bioscience and Environmental Technology, Centre for Organelle Research, Faculty of Science and Technology, University of Stavanger, Stavanger, Norway)
Material： Frontiers in Microbiology (Web)
Volume： 11  Page： 263  Publication year： 2020 
JST Material Number： U7080A  ISSN： 1664-302X  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The cellular methyl donor S-ad...

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Thesaurus term： Methylation ,  *relaxation phenomenon ,  *gene ,  *mutagenesis ,  wild type ,  *Escherichia coli ,  *oxidation ,  sparger ,  substrate (biochemistry) ,  active site ,  enzyme ,  in vitro experiment ,  DNA ,  DNA glycosylase ,  mutation rate ,  *microorganism

Author keywords (5)： 5-formyluracil ,  oxidized base repair ,  base substitution ,  AlkA ,  DNA glycosylase

JST classification (5)： Gene manipulation  (EC02050B) ,  Gene expression  (EC02040Q) ,  Physiology and pathogenicity of microbial infection  (EG03053T) ,  Infectious diseases,parasitics diseases in general.  (GD01010H) ,  Microorganism biochemistry  (EG03020N)

Reference (80)：

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• Berquist B. R., Wilson D. M. III (2012). Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett. 327 61-72. doi: 10.1016/j.canlet.2012.02.001

Terms in the title (6)： Escherichia ,  遺伝子 ,  酸化 ,  変異誘発 ,  緩和 ,  活性化