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J-GLOBAL ID：202002287241949663   Reference number：20A1018624

Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering of Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase

Methanomethylophilus alvusピロリジル-tRNAシンテターゼの構造に基づく工学による完全生産性無細胞遺伝コードの拡大【JST・京大機械翻訳】

Author (8)： Seki Eiko (Structural Biology Laboratory, RIKEN) ,  Seki Eiko (RIKEN Cluster for Science, Technology and Innovation Hub, RIKEN) ,  Yanagisawa Tatsuo (Structural Biology Laboratory, RIKEN) ,  Yanagisawa Tatsuo (Laboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research (BDR), RIKEN) ,  Kuratani Mitsuo (Structural Biology Laboratory, RIKEN) ,  Sakamoto Kensaku (Laboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research (BDR), RIKEN) ,  Yokoyama Shigeyuki (Structural Biology Laboratory, RIKEN) ,  Yokoyama Shigeyuki (RIKEN Cluster for Science, Technology and Innovation Hub, RIKEN)
Material： ACS Synthetic Biology
Volume： 9  Issue： 4  Page： 718-732  Publication year： 2020 
JST Material Number： W5048A  ISSN： 2161-5063  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Pyrrolysyl-tRNA synthetase (Py...

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Thesaurus term： crystal structure ,  amino acid ,  *tRNA ,  *Heredity ,  Proteins ,  Mutation ,  Ricin ,  binding site ,  Methanosarcina barkeri ,  Protein Engineering ,  *synthase ,  *Genetic Code ,  Methanosarcina mazei ,  cell- free protein synthesis ,  antibody fragment ,  microorganism ,  Methanogens

Author keywords (6)： cell-free protein synthesis ,  non-canonical amino acid ,  pyrrolysyl-tRNA synthetase ,  Methanomethylophilus alvus ,  structure-based protein engineering ,  Herceptin-Fab

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (6)： tRNA ,  シンテターゼ ,  工学 ,  細胞 ,  遺伝 ,  拡大