Art

J-GLOBAL ID：202002287514229736   Reference number：20A0627427

S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells

S100A9は骨細胞様細胞におけるMAPKおよびSTAT3シグナル伝達経路を介してIL-6およびRANKL発現を増加させる【JST・京大機械翻訳】

Author (7)： Takagi Ryosuke ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Sakamoto Eijiro ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Kido Jun-ichi ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Inagaki Yuji ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Hiroshima Yuka ( Department of Oral Microbiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Naruishi Koji ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan) ,  Yumoto Hiromichi ( Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8504, Japan)
Material： BioMed Research International (Web)  (BioMed Res Int (Web))
Volume： 2020  Page： Null  Publication year： 2020 
JST Material Number： U7008A  ISSN： 2314-6133  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Objective. Calprotectin is a h...

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Thesaurus term： phosphorylation ,  chemokine ,  *interleukin 6 ,  *MAP kinase ,  Western blotting ,  siRNA ,  inflammatory cytokine ,  monocyte ,  neutrophils ,  complex(substance) ,  interleukin 1 ,  *cellular signal transduction ,  *RANKL ,  TNF alpha ,  ELISA

JST classification (4)： Mouth(=oral cavity),esophagus  (EJ06020R) ,  Basic medicine on musculoskeletal system  (GG01020B) ,  Diseases of tooth and mouth(=oral cavity)  (GT03000G) ,  Digestive system diseases  (GH03000W)

Reference (47)：

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• F. Shabani, A. Farasat, M. Mahdavi, N. Gheibi, "Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer," Inflammation Research, vol. 67, no. 10, pp. 801-812, 2018.
• X. Sun, H. Meng, D. Shi et al., "Analysis of plasma calprotectin and polymorphisms of S100A8 in patients with aggressive periodontitis," Journal of Periodontal Research, vol. 46, no. 3, pp. 354-360, 2011.
• M. Pruenster, T. Vogl, J. Roth, M. Sperandio, "S100A8/A9: from basic science to clinical application," Pharmacology & Therapeutics, vol. 167, pp. 120-131, 2016.

Terms in the title (9)： S100A9 ,  骨 ,  細胞 ,  MAPK ,  STAT3 ,  シグナル伝達経路 ,  IL-6 ,  RANKL ,  発現