Art

J-GLOBAL ID：202002289521118251   Reference number：20A0573081

Metallointercalator [Ru(dppz)₂(PIP)]²⁺ Renders BRCA Wild-Type Triple-Negative Breast Cancer Cells Hypersensitive to PARP Inhibition

メタロインターカレータ[Ru(dppz)_2(PIP)]2+はPARP阻害に対して過敏なBrca野生型トリプルネガティブ乳癌細胞を提供する【JST・京大機械翻訳】

Author (11)： Yusoh Nur Aininie (Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia) ,  Leong Sze Wei (Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor, Malaysia) ,  Chia Suet Lin (Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor, Malaysia) ,  Chia Suet Lin (Institute of Bioscience, Universiti Putra Malaysia, Selangor, Malaysia) ,  Harun Siti Norain (Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia) ,  Rahman Mohd Basyaruddin Abdul (Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia) ,  Rahman Mohd Basyaruddin Abdul (Integrated Chemical Biophysics Research Centre, Faculty Science, Universiti Putra Malaysia, Selangor, Malaysia) ,  Vallis Katherine A. (Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, United Kingdom) ,  Gill Martin R. (Department of Chemistry, College of Science, Swansea University, Wales, United Kingdom) ,  Ahmad Haslina (Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia) ,  Ahmad Haslina (Integrated Chemical Biophysics Research Centre, Faculty Science, Universiti Putra Malaysia, Selangor, Malaysia)
Material： ACS Chemical Biology
Volume： 15  Issue： 2  Page： 378-387  Publication year： 2020 
JST Material Number： W5037A  ISSN： 1554-8937  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： There is a need to improve and...

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Thesaurus term： *hypersensitivity ,  clone ,  fibroblast ,  *tumor cell ,  cell proliferation ,  human(primates) ,  *breast tumor ,  complex(substance) ,  apoptosis ,  DNA double strand break ,  heredity ,  DNA replication ,  *wild type ,  potentiation ,  cell movement

JST classification (1)： Biological function  (EB03040U)

Terms in the title (6)： Ru ,  PARP ,  阻害 ,  野生型 ,  トリプルネガティブ乳癌 ,  細胞