Rsrc
J-GLOBAL ID:202010001537058410   Research Resource code:NBDC01952 Update date:Jul. 09, 2020

euL1db, the European database of L1-HS retrotransposon insertions in humans: euL1db

euL1db, the European database of L1-HS retrotransposon insertions in humans: euL1db
Resource classification: Database
Tag (subject)  (3): Genetic variation ,  Genome/Gene ,  Health/Disease
Tag (data type)  (2): Sequence ,  Bibliography/Documents
Species (1): Homo sapiens (NCBI Taxonomy ID: 9606)
Overview:
Retrotransposons, which comprises LINE, SINE and LTR-containing elements, accounts for almost half of our genome (Fig. 1). They are mobile genetics elements - also known as jumping genes - but only the L1-HS subfamily has retained the ability to jump autonomously in modern humans. Their mobilization in germline - but also some somatic tissues - contributes to human genetic diversity and to diseases, such as cancer. euL1db provides a curated and comprehensive summary of L1-HS insertion polymorphisms identified in healthy or pathological human samples and published in peer-reviewed journals. It will help understanding the link between L1 retrotransposon insertion polymorphisms and phenotype or disease.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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