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J-GLOBAL ID:202010001773428643   Research Resource code:NBDC02296 Update date:Jul. 09, 2020

Database of fuzzy protein complexes: FuzDB

Database of fuzzy protein complexes: FuzDB
Resource classification: Database
Tag (subject)  (1): Protein
Tag (data type)  (3): 3D structure ,  Interaction/Pathway ,  Bibliography/Documents
Species (1): All (NCBI Taxonomy ID: 1)
Overview:
FuzDB compiles experimentally observed fuzzy protein complexes, where intrinsic disorder (ID) is maintained upon interacting with a partner (protein, nucleic acid or small molecule) and directly impacts biological function. Entries in the database have both (i) structural evidence demonstrating the structural multiplicity or dynamic disorder of the ID region(s) in the partner bound form of the protein and (ii) in vitro or in vivo biological evidence that indicates the significance of the fuzzy region(s) in the formation, function or regulation of the assembly. Unlike the other intrinsically disordered or unfolded protein databases, FuzDB focuses on ID regions within a biological context, including higher-order assemblies and presents a detailed analysis of the structural and functional data.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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