J-GLOBAL ID:202010005615580140   Research Resource code:NBDC01940 Update date:Jul. 09, 2020

The Improved Database Of Chimeric Transcripts and RNA-Seq Data: ChiTaRS

The Improved Database Of Chimeric Transcripts and RNA-Seq Data: ChiTaRS
Resource classification: Database
Tag (subject)  (3): cDNA/EST ,  RNA ,  Health/Disease
Tag (data type)  (2): Sequence ,  Expression
Species (8): Bos taurus (NCBI Taxonomy ID: 9913) ,  Danio rerio (NCBI Taxonomy ID: 7955) ,  Drosophila melanogaster (NCBI Taxonomy ID: 7227) ,  Homo sapiens (NCBI Taxonomy ID: 9606) ,  Mus musculus (NCBI Taxonomy ID: 10090) ,  Rattus norvegicus (NCBI Taxonomy ID: 10116) ,  Saccharomyces cerevisiae (NCBI Taxonomy ID: 4932) ,  Sus scrofa (NCBI Taxonomy ID: 9823)
The ESTs and mRNAs from GenBank have been used to identify chimeric RNAs of two or more different genes. By analyzing thousands of chimeric ESTs by RNA sequencing, we found that the expression level of chimeric ESTs is generally low and they are highly tissue specific in normal cells. Here we present the improved version of the ChiTaRS database (ChiTaRS-3.1) of about 40,000 chimeric transcripts in humans, mice, fruit flies, zebrafishes, cows, rats, pig and yeast. In the current version we extended the experimental data evidence as well as included a novel type of the sense-antisense chimeric transcripts of the same gene confirmed experimentally by RT-PCR, qPCR, RNA-sequencing and mass-spec peptides. In addition, we collected about 11,700 human cancer breakpoints with the expression levels of chimeric RNAs confirmed by the paired-end RNA-sequencing experiments in different tissues in humans, mice and fruit flies.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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