J-GLOBAL ID:202010012779448630   Research Resource code:NBDC02135 Update date:Jul. 09, 2020

Deciphering the Mechanisms of Developmental Disorders: DMDD

Deciphering the Mechanisms of Developmental Disorders: DMDD
Owning Organization:
  • Francis Crick Institute
Resource classification: Data,Database
Tag (subject)  (3): Genome/Gene ,  Health/Disease ,  Organism
Tag (data type)  (4): Phenotype ,  Image/Movie ,  Method ,  3D structure
Species (1): Mus musculus (NCBI Taxonomy ID: 10090)
Initiated in 2013, DMDD has the ambitious goal of identifying all embryonic lethal knockout lines made at the Wellcome Trust Sanger institute, through their work as a major centre for creation of individual mouse gene knockouts. DMDD uses a combination of comprehensive 3D imaging, tissue histology, immunocytochemistry and transcriptomics to identify abnormalities in embryo and placental structure for each embryonic lethal line. All data is made freely available via this web site, enabling individual researchers to identify lines relevant to their own research. The DMDD programme is coordinating its work with similar international efforts through the umbrella of the International Mouse Phenotyping Consortium.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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