Rsrc
J-GLOBAL ID:202010014678013902   Research Resource code:NBDC02193 Update date:Mar. 29, 2019

Target Central Resource Database: TCRD

Target Central Resource Database: TCRD
Owning Organization:
  • European Commission under FP7 Grant Agreement
  • Icahn School of Medicine at Mount Sinai
  • UNM School of Medicine
  • University of Miami School of Medicine
Resource classification: Database
Tag (subject)  (2): Drug ,  Protein
Tag (data type)  (1): Interaction/Pathway
Species (1): Homo sapiens (NCBI Taxonomy ID: 9606)
Overview:
TCRD is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases, ion channels and nuclear receptors. Olfactory GPCRs (oGPCRs) are treated as a separate family. A key aim of the KMC is to classify the development/druggability level of targets. The official public portal for TCRD is Pharos (pharos.nih.gov). Based on modern web design principles the Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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