Rsrc
J-GLOBAL ID:202010018143423813   Research Resource code:NBDC02188 Update date:Mar. 29, 2019

mirDNMR: mirDNMR

mirDNMR: mirDNMR
Owning Organization:
  • Wenzhou Medical University
Resource classification: Database
Tag (subject)  (1): Genome/Gene
Tag (data type)  (1): Sequence
Species (1): Homo sapiens (NCBI Taxonomy ID: 9606)
Overview:
mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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