Rsrc
J-GLOBAL ID:202010018295105302   Research Resource code:NBDC02128 Update date:Mar. 29, 2019

Protein Protein Interaction Inhibition Database: 2P2Idb

Protein Protein Interaction Inhibition Database: 2P2Idb
Owning Organization:
  • Laboratory of Integrative Structural & Chemical Biology (iSCB)
Resource classification: Database
Tag (subject)  (1): Protein
Tag (data type)  (2): Interaction/Pathway ,  3D structure
Species (1): All (NCBI Taxonomy ID: 1)
Overview:
2P2Idb is a hand-curated structural database dedicated to the modulation of protein-protein interactions (PPIs).

It includes all interactions for which both the protein-protein and protein-modulator complexes have been structurally characterized by X-ray or NMR. The 2P2I database currently contains 14 protein-protein complexes, 16 free proteins, 56 protein-ligand complexes and 53 small molecule inhibitors. Only inhibitors found at the interface (orthosteric modulators) have been considered in this version of the database. The web server provides links to related sites of interest, binding affinity data, pre-calculated structural information about protein-protein interfaces and 3D interactive views through java applets.
Source: FAIRsharing
Record maintainer: See the corresponding part in the FAIRsharing record
Record license: Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license

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