Rchr
J-GLOBAL ID：202101000025518920   Update date: Aug. 11, 2024

NISHITANI-NAKAMURA TOMOE

NISHITANI-NAKAMURA TOMOE
Research field  (1)： Physiology
Research keywords  (12)： survival factor ,  learning and memory ,  electrophysiology ,  cultured cardiomyocytes ,  Energy metabolism ,  Ca2+ sensor ,  immature heart ,  neuronal function ,  heart function ,  transporter ,  ion channel ,  Ca2+ signal
Research theme for competitive and other funds  (46)：
  • 2024 - 2028 川崎病の本質解明と個別最適な治療戦略開発に資する症例コホート長期追跡研究の樹立
  • 2024 - 2025 ミトコンドリア機能異常と心肺疾患との関連、運動療法の効果の検討
  • 2024 - 2025 和歌山県の心疾患予防への新アプローチ:加熱式タバコ vs 紙巻きタバコの循環器系に対する健康リスクの比較分析
  • 2022 - 2025 Clarification of a novel calcium signaling pathway that suppresses obesity
  • 2023 - 2024 Role of K+ channel regulator NCS-1 in pain relief during neuropathy and related signals during neuropathy
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Papers (53)：
  • Sakiko Matsumura, Jumpei Yasuda, Takuya Notomi, Yoshihiro Suzuki, I-Shan Chen, Daichi Murakami, Muneki Hotomi, Tomoe Y. Nakamura. Direct toxicity of cigarette smoke extract on cardiac function mediated by mitochondrial dysfunction in Sprague-Dawley rat ventricular myocytes and human induced pluripotent stem cell-derived cardiomyocytes. PLoS One. 2024
  • I-Shan Chen, Jumpei Yasuda, Takuya Notomi, Tomoe Y. Nakamura. Licorice metabolite 18β-glycyrrhetinic acid activates G protein-gated inwardly rectifying K+ channels. British Journal of Pharmacology. 2023. 1-17
  • Ivan Gando, Manuel Becerra Flores, I-Shan Chen, Hua-Qian Yang, Tomoe Y Nakamura, Timothy J Cardozo, William A Coetzee. CL-705G: a novel chemical Kir6.2-specific KATP channel opener. Frontiers in pharmacology. 2023. 14. 1197257-1197257
  • Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y Nakamura, Mei-Chuan Ko, Shiroh Kishioka. Chemogenetic activation of central gastrin-releasing peptide-expressing neurons elicits itch-related scratching behavior in male and female mice. Pharmacology research & perspectives. 2021. 9. 3. e00790
  • Tomoe Y, NAKAMURA-NISHITANII. Divergent functions of neuronal Ca2+ sensor-1(NCS-1),a novel regulator of Ca2+ signals in excitable tissues, and their relation to various diseasesoe of. J Wakayama Med. Soc. 2021. 72. 4. 192-197
ｍore...
MISC (2)：
  • Tomoe Y. Nakamura-Nishitani, Shu Nakao, Shigeo Wakabayashi. Cardioprotective Roles of Neuronal Ca2+ Sensor-1 during Stress. BIOPHYSICAL JOURNAL. 2015. 108. 2. 609A-609A
  • 西谷友重. Oh NO! NOが筋ジストロフィーの原因となる!. 蛋白質核酸酵素 PNE. 2009. 54. 7. 852
Patents (1)：
  • トランスジェニック非ヒト動物
Books (24)：
  • 研究者の多様性を阻む;無意識のバイアス;を意識的に外してみよう
    実験医学・羊土社 2023
  • A novel Ca2+ regulatory mechanism specific for immature hearts and its potential as a therapeutic target
    2021
  • 幼少期の心機能を制御する新しいCa2+調節タンパク質の発見とその分子機構
    日本小児循環器学会雑誌 ・日本小児循環器学会 2014
  • 子どもの心臓収縮と心肥大を調節する新しい制御蛋白質NCS-1
    循環器病研究の進歩(通巻52号)・共和企画 2012
  • Oh NO! NOが筋ジストロフィーの原因となる!
    蛋白質核酸酵素 PNE・共立出版 2009
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Lectures and oral presentations  (67)：
  • Regulation of mitochondrial function by an intracellular Ca2+ sensor is cr function by an intracellular Ca2+ sensor is critical for myocardial
    (The 100th Anniversary Annual Meeting of The Physiological Society of Japan 2023)
  • Protective effect of the conditioned medium from human adipose-derived stem cell culture on oxidative stress-induced cytotoxicity in primary cultured rat cardiomyocytes and human iPS cell-derived cardiomyocytes
    (The 100th Anniversary Annual Meeting of The Physiological Society of Japan 2023)
  • Effects and mechanisms of glycyrrhizic acid (a main component of licorice) and its metabolite on GIRK channel activity and its mechanism of action
    (The 100th Anniversary Annual Meeting of The Physiological Society of Japan 2023)
  • Effects of Cigarette Smoke Extracts (Combustible and Heated Tobacco) on Rat and Human iPS Cell-Derived Cardiomyocytes
    (BPS 2023 - Biophysical Society Annual Meeting 2023)
  • A novel KIR-specific KATP channel opener
    (BPS 2023 - Biophysical Society Annual Meeting 2023)
ｍore...
Education (3)：
  • 1992 - 1995 Okayama University
  • 1995 - Okayama University The Graduate School of Natural Science and Technology Ph.D. in Pharmaceutical Science
  • - 1989 Okayama University Faculty of Pharmaceutical Sciences Department of Pharmacy
Work history (7)：
  • 2020/01 - 現在 Wakayama Medical University Pharmacology Professor
  • 2004/04 - 2009 National Cerebral and Cardiovascular Center, Research Institute Molecular Physiology Laboratory Chief
  • 2002/08 - 2004 Kyushu University Faculty of Medical Sciences COE Postdoctoral Fellow
  • 1999/08 - 2002 New York University School Pediatric Cardiology Assistant Professor
  • 1997/10 - 1999 National Cerebral and Cardiovascular Center, Research Institute JST (Japan Science and Technology) Special Research Scientist
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Committee career (22)：
  • 2024/04 - 現在 日本薬理学会 研究推進委員会委員
  • 2024/04 - 現在 自然科学研究機構生理学研究所 運営会議共同利用研究部会委員
  • 2024/04 - 現在 自然科学研究機構生理学研究所 運営会議委員
  • 2024/04 - 現在 日本学術会議 連携会員(IUPHAR分科会)
  • 2024/04 - 現在 日本学術会議 連携会員(機能医科学分科会 幹事)
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Awards (2)：
  • 2014 - 国立循環器病研究センター ジョイントプロジェクト賞
  • 2012 - 日本生理学会 第2回入澤彩記念女性生理学賞
Association Membership(s) (7)：
Biophysical Society ,  アメリカ心臓協会 ,  国際心臓研究学会 ,  日本生化学会 ,  日本循環薬理学会 ,  日本生理学会 ,  日本薬理学会
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